The Comparison of Tunnel Morphology and Graft Healing in Anterior Cruciate Ligament Reconstructions Using Peroneus Longus And Hamstring Tendons
Anterior Cruciate Ligament Rupture
De qué trata este estudio
El registro no identifica actualmente este estudio como reclutando. Consulta su estado antes de planificar una evaluación.
- Tipo de estudio
- De intervención
- Fase
- No aplica
- Rango de edad
- 18 años - 45 años
- Sexo admitido
- Todos los sexos
- Voluntarios sanos
- No aceptados
- Participantes
- 58 Real
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Las explicaciones y la navegación están en español. Los textos proporcionados por el registro, incluidos títulos, resúmenes y criterios, se conservan en su idioma original. Puedes pedir orientación en español a WCR.
Acerca de la investigación
1. Comparison of the grafts using Magnetic Resonance Imaging (MR) to determine whether their maturation and bone integration are different,
2. Comparison of the grafts using Computerized Tomography (CT) to determine whether their effects on the tunnels opened in cruciate ligament reconstruction surgeries are different,
3. In the event that graft healing and effects on the tunnels differ between grafts, determination of whether these differences are related to patient clinics,
Leer la descripción completa
The project method; Patients who will be operated with 2 different grafts used in anterior cruciate ligament surgeries will be included in 2 different randomized groups of 29 people (hamstring and peroneus groups) determined by obtaining their informed consent before the surgery and then,
1. The maturation of the grafts will be measured and compared with the SNQ (Signal/Noise quotient) value and the graft-bone integration with the measuring Tendon Bone Healing Grade with the Magnetic Resonance (MR) to be taken at the 1st year controls after the surgery,
2. Changes in tunnel morphology; The volume of the tunnels will be measured with the Computerized Tomography (CT) imaging method to be taken prospectively within the first week after the surgery date and 1 year after the surgery date and the changes within 1 year will be calculated by comparing them.
3. In the outpatient clinic follow-ups of both groups; Knee laxity will be obtained with Lachman, Anterior drawer and Pivot shift tests and knee scores and activity levels will be obtained using IKDC, Lysholm, Marx activity scales and it will be examined whether these data are related to SNQ, Tendon Bone Healing Grade and tunnel expansion.
¿Quién podría participar?
La lista siguiente contiene el texto del patrocinador. Puede incluir condiciones, tratamientos previos, resultados de pruebas y otros requisitos. Aparecer en tu búsqueda no significa que califiques.
Inclusion Criteria:
- Patients aged between 18 and 45 years.
- BMI in the range of 18 to 28.
- Diagnosed with an anterior cruciate ligament (ACL) injury preoperatively confirmed by MRI.
- Patients for whom it is deemed appropriate to harvest ipsilateral hamstring tendons or Peroneus Longus tendon for use as a graft.
Exclusion Criteria:
- History of previous surgery on the affected knee or ankle.
- Presence of multiple ligament injuries in the affected knee.
- ACL injuries that occurred more than 12 months prior to surgery.
- Evidence of unstable meniscal injury on preoperative MRI that may alter the -postoperative rehabilitation protocol.
- Inability to obtain a graft diameter of at least 9 mm using the isolated graft.
- Presence of meniscal tears requiring repair.
- Presence of advanced chondral lesions requiring surgical intervention.
- Intraoperative detection of multiple ligament injuries.
- Requirement for additional surgical procedures that would alter the standard rehabilitation protocol.
- Occurrence of intraoperative surgical complications.
Tratamiento, grupos y participación
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- Asignación
- Asignación al azar
- Enmascaramiento
- Enmascaramiento simple
Peroneus Longus Group
Participants who underwent ACL reconstruction using Peroneus Longus tendon graft.
Procedure: Surgical procedure using Peroneus Longus for ACL reconstruction.
Hamstring Group
Participants who underwent ACL reconstruction using Hamstring tendon graft.
Procedure: Surgical procedure using Hamstring tendons for ACL reconstruction.
Surgical procedure using Peroneus Longus for ACL reconstruction. PROCEDURE
Surgical procedure using Peroneus Longus for ACL reconstruction.
Surgical procedure using Hamstring tendons for ACL reconstruction. PROCEDURE
Surgical procedure using Hamstring tendons for ACL reconstruction.
Qué evalúan los investigadores
Estas medidas indican qué se estudia. No prueban que un tratamiento funcione.
Medidas principales
Graft Maturation Assessed by Signal-to-Noise Quotient (SNQ) on MRI
Plazo: 1 year postoperatively.
Comparison of graft maturation between peroneus longus and hamstring tendon autografts using SNQ values obtained from 1-year postoperative MRI.
Tendon-Bone Healing Assessed by MRI Grading System
Plazo: 1 year postoperatively.
Comparison of graft-bone integration between peroneus longus and hamstring tendon autografts using MRI Grading System obtained from 1-year postoperative MRI.
Change in Tunnel Volume Assessed by CT
Plazo: Within 1 week post-surgery and at 1 year post-surgery.
Comparison of tunnel volume changes between peroneus longus and hamstring tendon autografts by measuring tunnel volume via CT imaging performed within the first week and 1 year after surgery.
Medidas secundarias
Knee Laxity Assessed by Clinical Tests
Plazo: At 1-year follow-up.
Comparison of knee laxity (Lachman, anterior drawer, and pivot shift tests) between groups and correlation with graft healing (SNQ, Tendon bone healing grade) and tunnel expansion.Clinical grading of laxity based on standard examination protocols.
Patient-Reported Knee Function and Activity Levels
Plazo: At 1-year follow-up.
Comparison of knee function and activity levels between groups using IKDC, Lysholm, and Marx scales and evaluation of correlations with SNQ, Tendon bone healing grade, and tunnel volume changes.Standardized scoring from IKDC, Lysholm, and Marx Activity scales.
Relationship Between Tunnel Changes and Clinical Outcomes
Plazo: At 1-year follow-up.
Assessment of whether tunnel volume changes correlate with knee function, activity levels, or laxity test results.Statistical correlation analysis between tunnel volume changes and clinical outcomes.
Comparison of Graft Healing and Tunnel Changes Between Groups
Plazo: 1 year postoperatively.
Evaluation of whether differences in SNQ, Tendon bone healing grade, or tunnel volume changes are specific to patient demographics or clinical characteristics.
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Abrir resultados oficiales ↗Centros de investigación (1)
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1 centros
Karadeniz Technical University, Orthopedic and Traumatology DepartmentTrabzon, Turkey (Türkiye)Estado desconocido
Equipo y fechas
- Patrocinador principal
- Karadeniz Technical University
- Inicio del estudio
- 1 ene 2025 Real
- Finalización primaria
- 1 jun 2026 Real
- Finalización del estudio
- 1 jun 2026 Real
- Primera publicación
- 10 ene 2025 Real
- Última actualización
- 10 nov 2026 Real
Contactos oficiales del estudio
No hay un contacto central indicado. Revisa los centros y el registro oficial.
Título oficial del estudio
The Comparison of Tunnel Morphology and Graft Healing in Anterior Cruciate Ligament Reconstructions Using Peroneus Longus And Hamstring Tendons
Consulta a Wellness Clinical Research
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Fuente: API v2 de ClinicalTrials.gov. Patrocinadores e investigadores envían la información. La NLM no aprueba la seguridad ni la ciencia de todos los estudios registrados. Aviso del registro.
Consultado: 12 nov 2026 · Última actualización del registro: 10 nov 2026