Records are supplied by study sponsors and investigators. A registry listing is not an endorsement or a guarantee of safety, availability or eligibility.
WCR feed checked: Nov 11, 2026.
RecruitingNCT06439082
Sickle Cell Disease
Phase 312 years - 100 yearsBirmingham, Alabama, United States +31 A phase III, multi-center, randomized, placebo-controlled, double-blind study to assess efficacy and safety of crizanlizumab (5 mg/kg) versus placebo, with or without hydroxyurea/hydroxycarbamide therapy, in adolescent and adult Sickle Cell Disease p…
CompletedNCT01352962
Urethral Neoplasms · Neoplasms, Urethral · Cancer of the Urethra · Urethral Cancer
Phase 118 years - Not specifiedBethesda, Maryland, United States Background: \- Gemcitabine and carboplatin are chemotherapy drugs used to treat several types of cancer, including cancer of the pancreas, bladder, ovaries, and lung. Lenalidomide, a drug that prevents the growth of new blood vessels in tumors, has b…
SuspendedNCT06876142
Multiple Myeloma · Relapsed and/or Refractory Multiple Myeloma (RRMM)
Phase 1 / Phase 218 years - 120 yearsBethesda, Maryland, United States Background: Multiple myeloma (MM) is a type of blood cancer that affects a person s immunity. MM returns after treatment (relapse) in almost all people; MM may also not respond to initial treatment (refractory). Many people with relapsed refractory M…
Not yet recruitingNCT07646210
Advanced Heart Failure · Ischemic Heart Failure
Phase 1 / Phase 218 years - 75 yearsHouston, Texas, United States This clinical study will evaluate the safety and tolerability of HiCM-188, an investigational allogeneic induced pluripotent stem cell (iPSC)-derived cardiomyocyte therapy, in adults with advanced heart failure who are undergoing coronary artery bypa…
Not yet recruitingNCT07549490
Acute Pain
Not applicable18 years - 100 yearsBethesda, Maryland, United States This pilot study will test an innovative way to establish how pain medicines provide analgesia in healthy adults. The study uses a group of short, controlled pain tests to look at different types of pain responses in the body. The main goal is to fin…
RecruitingNCT05925959
Abdominal Wall Hernia
Not applicable18 years - Not specifiedChicago, Illinois, United States +1 The goal of this randomized controlled trial is to compare preoperative intensive weight management to upfront surgery in obese patients undergoing complex abdominal wall reconstruction. The main question is will abdominal wall specific quality of li…
Not yet recruitingNCT07930013
Stroke
Not applicable18 years - Not specifiedLocation not listed The goal of this clinical trial is to learn if a very-low-field MRI scanner (0.064 Tesla), combined with artificial intelligence (AI) image enhancement, can accurately diagnose acute ischemic stroke in adults with suspected stroke. Healthy adult volu…
RecruitingNCT07757880
Cardiac Surgery
Not applicable18 years - Not specifiedBoston, Massachusetts, United States We are studying whether waking patients up and removing the breathing tube (also known as "extubation") in the operating room after cardiac surgery improves postoperative recovery without causing harm.
CompletedNCT04413279
Dry Eye Syndromes
Phase 4Not specified - Not specifiedIndianapolis, Indiana, United States To evaluate the benefit of treatment with a physician administered intracanalicular dexamethasone insert in evaporative dry eye disease (DED) patients with meibomian gland disfunction (MGD) and underlying inflammation undergoing LipiFlow Thermal Puls…
RecruitingNCT06819189
Healthy Volunteer
Phase 121 years - 60 yearsBethesda, Maryland, United States Background: Alcohol use disorder (AUD) can damage people s health, work, and family. Researchers want to know more about why some people are more vulnerable to AUD than others. The ZIP8 gene may be linked to an increased risk of AUD. Researchers want…
RecruitingNCT07761910
Non Small Cell Lung Cancer · Cardiotoxicity · Locally Advanced Non-Small Cell Lung Cancer · Radiation Therapy
Phase 218 years - Not specifiedIndianapolis, Indiana, United States Prospective clinical study designed to evaluate damage to the heart after receiving standard of care chemotherapy and radiation therapy for locally advanced Non-Small Cell Lung Cancer (NSCLC).
Not yet recruitingNCT06767124
Alzheimer Disease and Related Dementias (ADRD)
Not applicable21 years - Not specifiedLondon, Ontario, Canada It is projected that by 2030, one in every five Americans will be of retirement age, and this demographic shift is expected to result in more people suffering from dementia. A key feature of the brain is its need for a constant supply of glucose and …
Retrieved from ClinicalTrials.gov: Nov 12, 2026. Overall study status may differ from a particular location’s status.
