Analysis of the Positivity Rate of Sector-based Whole-body CT Scans in Grade C Trauma Patients in Essonne
Multiple Trauma/Injuries · Wounds and Injuries
What this study involves
The registry does not currently label this study as recruiting. Ask about its status before planning a screening visit.
- Study type
- Observational
- Phase
- Not applicable / not listed
- Age range
- 18 years - Not specified
- Sex eligible
- All sexes
- Healthy volunteers
- Not accepted
- Participants
- 100 Estimated
These are starting points, not an eligibility decision. The research team must review the full requirements.
About the research
Background: Grade C trauma patients show no obvious severe injury at first assessment, but the mechanism or circumstances of the accident make serious lesions possible. Guidelines recommend a whole-body CT scan as first-line imaging1. The organization of the French trauma system varies between regions2. Île-de-France distinguishes level 1 trauma centers, which are authorized to manage the most severe patients, from level 2 hospitals, which can perform a full injury assessment3. Essonne has no level 1 trauma center, and most are located in Paris. Emergency dispatch physicians must therefore choose between performing the scan at the local hospital or transporting the patient directly to a trauma center. When a local scan is abnormal, specialist consultation, image transfer and secondary transport take time (median of about 6 hours4) and may worsen the prognosis.
Objective: To assess whether the proportion of abnormal whole-body CT scans in grade C trauma patients justifies systematic transport to a trauma center rather than local imaging.
Methods: Retrospective, multicenter cohort study of about 100 adult grade C trauma patients managed by an Essonne mobile emergency team (SMUR) in 2025 who underwent a whole-body CT scan. We will determine the proportion of abnormal scans, whether the lesions could be managed locally or required a level 1 or 2 trauma center, the secondary transfer rate, and the time to final destination.
Hypothesis: The proportion of abnormal scans, particularly those requiring specific medical care, is high enough to support performing the first whole-body CT scan at a trauma center.
Read the full description
Grade C trauma patients are a diagnostic and logistical challenge: their initial presentation is reassuring, yet the mechanism of injury may conceal severe lesions, which is why whole-body CT is recommended as first-line imaging6. The destination chosen at the pre-hospital stage therefore determines both the speed of diagnosis and the speed of access to specialized care. In Essonne, where no level 1 trauma center exists, this choice is made by the SAMU dispatch physician, case by case, without local data on how often a scan performed at the sector hospital reveals lesions requiring specialized management. The delays reported after an abnormal local scan are the main argument for direct transfer, while the unnecessary mobilization of resources and the transport of patients who turn out to have normal scans are the main argument against.
This is a retrospective, multicenter, observational cohort study. It covers hospitals of the Essonne department that received grade C trauma patients managed by an Essonne SMUR team in 2025 and who received a whole-body CT. Cases will be identified from SMUR and SAMU activity records, then linked to the receiving hospitals' medical files. No intervention will be performed and no change to patient care is planned.
Data will be extracted from SAMU dispatch records, emergency department files and radiology reports. Variables will include:
- demographics and relevant medical history
- mechanism of injury and pre-hospital clinical findings
- time stamps for each care step (SMUR arrival on scene, hospital arrival, scan, specialist consultation, secondary transport, arrival at final destination)
- whole-body CT findings
- the level of care needed (local hospital, level 2 or level 1 trauma center)
- secondary transfers, and the regulation time required for them
Data will be recorded in a pseudonymized, secure database. Descriptive statistics will be used for the whole cohort. The proportion of abnormal whole-body CT scans will be reported with its 95% confidence interval.
Who may be able to participate?
The list below is the sponsor’s full registry wording. It can include conditions, prior treatment, test results and other requirements. A match in search does not mean you qualify.
Inclusion Criteria:
- Age over 18 years
- Grade C trauma patient managed between 01/01/2025 and 31/12/2025
- Having undergone a whole-body CT scan
- Attended by an Essonne SMUR team
Exclusion Criteria:
- Trauma patient meeting grade A or B criteria
- Low-kinetic accident and/or patient without an at-risk medical background
- No on-scene SMUR intervention
- Refusal of transport
- Taken to a level 1 trauma center as first-line destination
- Patient who objected to the use of their data
Study population
Adult grade C trauma patients attended on scene by a mobile emergency and resuscitation team (SMUR) of Essonne between 01/01/2024 and 31/12/2025, who underwent a whole-body CT scan at the sector hospital. Grade C patients are stable at first assessment, with no obvious severe injury, but their mechanism of injury and/or medical background make severe lesions possible. Patients are identified from the Essonne SAMU dispatch software and from the medical records of the emergency departments of the participating hospitals.
Understand screeningTreatment, groups and participation
The registry may describe treatments and study duration without a complete visit calendar. Ask the study team for the exact schedule, procedures, risks, costs and alternatives. Keep your usual care plan unless your treating clinician tells you otherwise.
- Assignment
- Not reported
- Masking
- Not reported
Grade C trauma patients with sector whole-body CT
Adult (\>18 years) grade C trauma patients attended on scene by an Essonne SMUR team between 01/01/2025 and 31/12/2025, who underwent a whole-body CT scan at the sector hospital. A grade C patient is stable (no hemodynamic disorder) and meets no grade A or B criterion, but has a high-risk mechanism of injury (fall of more than 6 m, ejected, crushed, thrown or blasted victim, death of a passenger in the same vehicle, proximal open limb fracture or closed fracture of at least 2 long bones) and/or an at-risk medical background.
Diagnostic Test: Whole-body CT scan at the sector hospital
Whole-body CT scan at the sector hospital DIAGNOSTIC_TEST
Whole-body computed tomography performed as first-line imaging in the radiology department of the sector hospital covering the accident site, as part of routine care. Its results (trauma-related lesions, level of care required, secondary transfer to a trauma center) are analysed retrospectively.
What researchers are measuring
Outcome measures describe what is being studied. They are not proof that a treatment works.
Primary measures
Proportion of pathological whole-body CT scans
Time frame: at day 0
A whole-body CT scan is considered pathological if it shows trauma-related lesions on imaging, whatever their severity. Lesions discovered incidentally or present before the accident are not counted. Data are collected from the Essonne SAMU dispatch software and, for missing data, by calling the receiving emergency departments of the sector hospitals.
Secondary measures
Rate of secondary transfers to a trauma center
Time frame: at day 0
Final orientation of patients with a pathological whole-body CT scan, analysed qualitatively: proportion of patients secondarily transferred to a level 1 trauma center or an intensive care unit, and distribution between patients who can be managed at the sector hospital and those requiring care in a level 1 or level 2 trauma center.
Total time from initial SMUR care to arrival at the final destination
Time frame: at day 0
Total duration between the initial SMUR care and the arrival of the patient at the final destination, used to evaluate the impact of under-triage of grade C trauma patients by comparison of delays (Wilcoxon test). Delays are described as medians with interquartile ranges.
Proportion of pathological whole-body CT scans according to the collected variables
Time frame: at day 0
Descriptive analysis of the cohort of grade C trauma patients: proportion of pathological scans according to age, sex, medical background, type of accident and the criterion defining grade C.
Review the complete result tables and limitations in the official record.
Open official results ↗Research locations (1)
The overall study status and a local site’s status can differ. Confirm that location’s availability before traveling.
1 locations
Centre Hospitalier Sud FrancilienCorbeil-Essonnes, France, FranceStatus unknown
Study team and timeline
- Lead sponsor
- Centre Hospitalier Sud Francilien
- Study start
- Nov 15, 2026 Estimated
- Primary completion
- Nov 15, 2027 Estimated
- Study completion
- Nov 15, 2027 Estimated
- First posted
- Nov 10, 2026 Actual
- Last updated
- Nov 10, 2026 Actual
Official study contacts
Official study title
Analysis of the Positivity Rate of Sector-based Whole-body CT Scans in Grade C Trauma Patients in Essonne
Ask Wellness Clinical Research
Your message goes to WCR, including when this study is run by another organization. WCR may offer general guidance but may not operate this trial, have access to its team or be able to enroll you.
Source: ClinicalTrials.gov API v2. Information is submitted by sponsors and investigators. NLM does not approve the safety or science of all listed studies. Registry disclaimer.
Retrieved: Nov 12, 2026 · Last registry update: Nov 10, 2026
