Observation and Interactions Between Cardio-respiratory and Motor Transitions During Maximal Incremental Exercise Test on Elliptical Bike and Running Treadmill.

What this study involves

The registry does not currently label this study as recruiting. Ask about its status before planning a screening visit.

Study type

Observational

Phase

Not applicable / not listed

Age range

18 years - 64 years

Sex eligible

All sexes

Healthy volunteers

Accepted

Participants

20 Estimated

These are starting points, not an eligibility decision. The research team must review the full requirements.

About the research

For safety considerations and to ensure the effectiveness of physical activity within a rehabilitation programme, it is important to establish an appropriate exercise intensity to achieve the programme's objectives. This requires identifying individualised exercise intensity zones that are specifically tailored to each patient, in order to design an effective and progressive exercise training programme.

Exercise prescription is based on four principles: frequency, duration, volume, and intensity. The first three factors are relatively easy to adjust when planning a training programme, whereas exercise intensity is based on a concept that is more difficult to assess and control. On the one hand, exercise intensity is more complex to measure; on the other, establishing individualised reference points and guidelines tailored to each patient is not straightforward.

It is now well established that ventilatory transitions are individualised physiological markers that delineate exercise intensity zones. These transition markers provide valuable reference points for exercise training, helping to ensure that physical activity is both safe and sufficiently intense to induce beneficial physiological adaptations in patients.

Within this rehabilitation context, the aim of the present study is to identify markers of these two physiological transitions during a maximal exercise test conducted under laboratory conditions. The study seeks to identify non-invasive markers related to cardiovascular, respiratory, and motor responses, with a view to conducting similar assessments under real-world conditions in the future. A database has already been established using cycle ergometry (the CAREMO protocol). The next step is to build a new database based on maximal exercise testing, this time using two different exercise modalities: the elliptical trainer and the treadmill. In addition to the new challenge of investigating the second ventilatory transition, the less constrained movement patterns associated with these exercise modalities require adaptations to the analysis methods in order to continue identifying changes in motor behaviour.

Who may be able to participate?

The list below is the sponsor’s full registry wording. It can include conditions, prior treatment, test results and other requirements. A match in search does not mean you qualify.

Inclusion Criteria:

• Men and women of 18 to 64 y-old
• Subject able to run on a treadmill and bike on an elliptical bike for 20minutes
• No contraindications to participating in physical exercise.
• No chronic cardiac or respiratory conditions.
• No locomotor disorders affecting the spine or lower limbs that are incompatible with physical activity.
• No recent injuries (within the previous two months) that would prevent participation in physical activity.
• Affiliation with a social security scheme.

Exclusion Criteria:

• Pregnant women (as determined by a urine pregnancy test) and breastfeeding women.
• Use of medication likely to significantly interfere with heart rate regulation, as assessed by the principal investigator.
• Individuals falling within the categories specified in Articles L. 1121-5 to L. 1121-8 of the French Public Health Code (Code de la santé publique). These include protected individuals, namely pregnant women, women in labour, breastfeeding mothers, individuals deprived of their liberty by judicial or administrative decision, individuals receiving psychiatric care under Articles L. 3212-1 and L. 3213-1 who do not fall under the provisions of Article L. 1121-8, individuals admitted to a healthcare or social care facility for purposes other than research, minors, and individuals subject to a legal protection measure or unable to express their consent.
• Personnel who have a hierarchical relationship with the principal investigator.
• Individuals currently subject to an exclusion period from another study.
• Individuals who would receive more than €6,000 in compensation for their participation in other research involving human participants during the 12 months preceding this study.

Study population

Healthy volunteers

Treatment, groups and participation

The registry may describe treatments and study duration without a complete visit calendar. Ask the study team for the exact schedule, procedures, risks, costs and alternatives. Keep your usual care plan unless your treating clinician tells you otherwise.

Assignment

Not reported

Masking

Not reported

What researchers are measuring

Outcome measures describe what is being studied. They are not proof that a treatment works.

Primary measures

Research locations (1)

The overall study status and a local site’s status can differ. Confirm that location’s availability before traveling.

1 locations

Study team and timeline

Lead sponsor

University Hospital, Grenoble

Study start

Nov 15, 2026 Estimated

Primary completion

Jan 15, 2027 Estimated

Study completion

Jan 31, 2027 Estimated

First posted

Nov 10, 2026 Actual

Last updated

Nov 10, 2026 Actual

Official study contacts