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Back to study searchNCT07781592
By invitationNCT07781592ClinicalTrials.gov record

Exercise Intensity and Heat Responses in Children and Youth

Body Temperature Changes · Heat Stress · Child Development · Heat · Physiological Stress

THE QUICK READ

What this study involves

The registry does not currently label this study as recruiting. Ask about its status before planning a screening visit.

Study type
Interventional
Phase
Not applicable
Age range
9 years - 25 years
Sex eligible
Female
Healthy volunteers
Accepted
Participants
12 Estimated

These are starting points, not an eligibility decision. The research team must review the full requirements.

About the research

Little is known about how children and youth regulate body temperature during exercise in the heat compared with young adults, including whether differences in whole-body heat exchange contribute to their responses. The goal of this clinical trial is to determine how exercise intensity affects thermoregulation in boys and girls aged 9-16 years compared with young adult men and women aged 20-25 years. Participants will complete three study visits in a hot environment of 36°C (degree Celcius (97°F, degree Farenheit)), performing light-, moderate-, and vigorous-intensity exercise corresponding to metabolic heat production of 120, 160, and 200 W/m² (w=watts, m=meter), respectively. During each visit, participants will complete four 15-minute bouts of exercise (i.e., bout 1, 2, 3 and 4 respectively) separated by 15-minute rest periods. Testing will be performed in a whole-body air calorimeter, a specialized chamber that precisely measures heat lost through evaporation and dry heat exchange and the amount of heat stored in the body. These measurements, together with core temperature and heart rate, will allow researchers to determine how increasing exercise intensity affects the body's ability to lose heat and whether these responses differ between children and youth and young adults.

Who may be able to participate?

The list below is the sponsor’s full registry wording. It can include conditions, prior treatment, test results and other requirements. A match in search does not mean you qualify.

Inclusion Criteria:

  • Healthy male or female.
  • Aged 9-16 years or 20-25 years.
  • Habitually active, defined as participating in regular physical activity at least 3 times per week for at least 20 minutes per session over the previous 6 months.
  • Able to understand and communicate in English or French.
  • For participants younger than 18 years, written parental or guardian consent and participant assent are required.

Exclusion Criteria:

  • Acute illness at the time of testing (e.g., cold, flu, or infection).
  • History of a chronic medical condition that may affect thermoregulation, cardiovascular function, or exercise capacity (e.g., cardiovascular disease, metabolic disorders, respiratory disease including asthma requiring regular medication, or neurological disorders).
  • Use of medications known to affect thermoregulation, hydration status, or cardiovascular responses.
  • History of heat-related illness (e.g., heat exhaustion or heat stroke).
  • Digestive abnormalities or gastrointestinal conditions that may contraindicate ingestion of a telemetry pill.
  • Any condition that, in the opinion of the investigators, would compromise participant safety or the integrity of the data.
Understand screening

Treatment, groups and participation

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Assignment
Random assignment
Masking
No masking
Low-intensity exercise

Participants will complete intermittent light-intensity exercise in a hot environment of 36°C (degree Celsius (97°F, degree Fahrenheit)). Exercise will be performed at a metabolic heat production of 120 W/m² (W=watts; m=meter) and will consist of four 15-minute exercise periods separated by 15-minute rest periods. Exercise workload will be individually adjusted to achieve the prescribed metabolic heat production.

Other: Low-Intensity Exercise in the Heat

Moderate-intensity exercise

Participants will complete intermittent moderate-intensity exercise in a hot environment of 36°C (97°F). Exercise will be performed at a metabolic heat production of 160 W/m² and will consist of four 15-minute exercise periods separated by 15-minute rest periods. Exercise workload will be individually adjusted to achieve the prescribed metabolic heat production.

Other: Moderate-Intensity Exercise in the Heat

Vigorous-intensity exercise

Participants will complete intermittent vigorous-intensity exercise in a hot environment of 36°C (97°F). Exercise will be performed at a metabolic heat production of 200 W/m² and will consist of four 15-minute exercise periods separated by 15-minute rest periods. Exercise workload will be individually adjusted to achieve the prescribed metabolic heat production.

Other: Vigorous-Intensity Exercise in the Heat

Low-Intensity Exercise in the Heat OTHER

Participants complete intermittent low-intensity exercise at a metabolic heat production of 120 W/m² (w=watts; m=meter) in a hot environment of 36°C (degree Celsius (97°F, degree Fahrenheit)).

Moderate-Intensity Exercise in the Heat OTHER

Participants complete intermittent moderate-intensity exercise at a metabolic heat production of 160 W/m² in a hot environment of 36°C (97°F).

Vigorous-Intensity Exercise in the Heat OTHER

Participants complete intermittent vigorous-intensity exercise at a metabolic heat production of 200 W/m² in a hot environment of 36°C (97°F).

Prepare your questions

What researchers are measuring

Outcome measures describe what is being studied. They are not proof that a treatment works.

Primary measures

Core temperature

Time frame: End of each of the four 15 minutes exercise bouts (average of last 5 minutes)

Core temperature indexed by visceral (telemetry pill) temperature

Secondary measures

Evaporative heat loss

Time frame: End of each of the four 15 minutes exercise bouts (average of last 5 minutes)

Evaporative heat loss as assessed using a direct air calorimeter.

Dry heat loss

Time frame: End of each of the four 15 minutes exercise bouts (average of last 5 minutes)

Dry heat loss as assessed using a direct air calorimeter.

Whole-body total heat loss

Time frame: End of each of the four 15 minutes exercise bouts (average of last 5 minutes)

Total heat loss (dry + evaporative) as assessed using a direct air calorimeter

Body Heat Storage

Time frame: Change from start to the end for each of the four 15 minutes exercise bouts

Heat stored in the body for each of the exercise bouts

Skin Temperature

Time frame: End of each of the four 15 minutes exercise bouts (average of last 5 minutes)

Skin temperature measured at 8-sites (forehead, chest, scapula, upper arm, forearm, hand, thigh, calf) with mean value calculated as weighted value of 8 sites - forehead, 7%; chest, 17.5%; scapula, 17.5%, upper arm, 7%; forearm, 7%; hand, 5%; thigh, 19%; and calf, 20%.

Change in skin temperature

Time frame: Change from start to the end for each of the four 15 minutes exercise bouts

Skin temperature measured at 8-sites (forehead, chest, scapula, upper arm, forearm, hand, thigh, calf) with mean value calculated as weighted value of 8 sites - forehead, 7%; chest, 17.5%; scapula, 17.5%, upper arm, 7%; forearm, 7%; hand, 5%; thigh, 19%; and calf, 20%.

Heart rate

Time frame: End of each of the four 15 minutes exercise bouts (average of last 5 minutes)

Measured continuously with chest-band device

Thermal Sensation Scale

Time frame: End of each of the four 15 minutes exercise bouts (average of last 5 minutes)

Thermal sensation will be assessed using the American Society of Heating, Refrigerating and Air-Conditioning Engineers (ASHRAE) 7-point scale ("0=neutral to 7=extremely hot")

No results are flagged as posted.

Review the complete result tables and limitations in the official record.

Open official results ↗

Research locations (1)

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1 locations

University of OttawaOttawa, Ontario, CanadaStatus unknown

Study team and timeline

Lead sponsor
University of Ottawa
Study start
Jul 21, 2026 Actual
Primary completion
Apr 30, 2027 Estimated
Study completion
Jun 30, 2027 Estimated
First posted
Aug 24, 2026 Actual
Last updated
Nov 10, 2026 Actual

Official study contacts

No central contact is listed. Check the locations and the official record.

Official study title

Effects of Exercise Intensity on Thermoregulation in the Heat in Children and Youth

A HUMAN NEXT STEP

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Source: ClinicalTrials.gov API v2. Information is submitted by sponsors and investigators. NLM does not approve the safety or science of all listed studies. Registry disclaimer.

Retrieved: Nov 12, 2026 · Last registry update: Nov 10, 2026