Comparison Between Eccentric Hamstring Training and Sprint-Specific Training
Healthy Adult · Athlete · Exercise Training · Sport · Running · Ultrasound Imaging
What this study involves
The registry says this study is recruiting. Individual locations may have different availability.
- Study type
- Interventional
- Phase
- Not applicable
- Age range
- 18 years - 25 years
- Sex eligible
- All sexes
- Healthy volunteers
- Accepted
- Participants
- 90 Estimated
These are starting points, not an eligibility decision. The research team must review the full requirements.
About the research
The purpose of this study is to compare the effects of an intensity-, volume-, and time under tension-matched eccentric hamstring exercise intervention with the Romanian deadlift (RDL) and the Nordic hamstring exercise (NHE) to a sprint-specific training program on hamstring muscle architecture, volume, sprint performance, strength, and power.
Participants will be assigned to complete one of the 3 hamstring interventions for 10 weeks.
Read the full description
Prior to the intervention, participants will undergo baseline testing which will include a) ultrasound imaging of the hamstrings muscles for measures of biceps femoris long head fascicle length, pennation angle, muscle thickness, anatomical cross-sectional area, and muscle volume b) passive and active ranges of motion, c) 3 repetition maximum (3RM) RDL strength, d) peak NHE force, e) countermovement jump height, f) broad jump distance, g) Pro Agility change of direction, and h) a 60 m sprint with sprint kinematics assessed via inertial measurement units.
Participants will be randomly assigned to either the RDL, NHE, or sprint training group. After randomization, each participant will undergo the intervention program based upon their group allocation.
Performance testing and imaging will be repeated mid-intervention, following the intervention, and after 2 weeks of deloading.
Who may be able to participate?
The list below is the sponsor’s full registry wording. It can include conditions, prior treatment, test results and other requirements. A match in search does not mean you qualify.
Inclusion Criteria:
- Age 18-25 years
- Actively participating in a club team
- \>6 months experience with resistance training
- Minimum of 1 year experience at the high school level in organized team sport
- No history of hamstring injury within the last 6 months
- No history of major lower extremity surgery (including back)
- No acute musculoskeletal injury to the lower extremity
- Not currently pregnant
Exclusion Criteria:
- Unable to refrain from resistance training outside the study
- Unable to make at least 80% of the training sessions
- Hamstring injury in the last 6 months
- History of major lower extremity surgery (including back)
- Acute musculoskeletal injury to the lower extremity
- Currently pregnant
Treatment, groups and participation
The registry may describe treatments and study duration without a complete visit calendar. Ask the study team for the exact schedule, procedures, risks, costs and alternatives. Keep your usual care plan unless your treating clinician tells you otherwise.
- Assignment
- Random assignment
- Masking
- Double masked
Romanian dead lift (RDL) group
The training intervention groups will undergo the same program with the only difference being the interventional hamstring exercise. The program will consist of a 2-week familiarization period followed by 8 weeks of progressive training. The RDL arm will perform RDL.
Other: RDL
Nordic hamstring exercise (NHE) group
The training intervention groups will undergo the same program with the only difference being the interventional hamstring exercise. The program will consist of a 2-week familiarization period followed by 8 weeks of progressive training. The NHE arm will performed NHE
Other: NHE
Sprint group
The training intervention groups will undergo the same program with the only difference being the interventional hamstring exercise. The program will consist of a 2-week familiarization period followed by 8 weeks of progressive training. The sprint training program will be performed twice per week with the first day of training focused on shorter distances to focus on acceleration and the second training day focused on maximal velocity. The relative efforts and distances for each training day will mimic a similar prescription to that of the resistance training program.
Other: Sprint testing
RDL OTHER
The RDL will be performed with a 6 second eccentric component with the athlete returning to the start position with a maximal concentric hip extension.
NHE OTHER
The NHE will be performed with a 6 second eccentric component.
Sprint testing OTHER
The sprint training program will be performed twice per week with the first day of training focused on shorter distances to focus on acceleration and the second training day focused on maximal velocity. The relative efforts and distances for each training day will mimic a similar prescription to that of the resistance training program.
What researchers are measuring
Outcome measures describe what is being studied. They are not proof that a treatment works.
Primary measures
Change in fascicle length (FL)
Time frame: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)
Not reported in this registry record.
Change in muscle cross-sectional area (CSA)
Time frame: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)
Not reported in this registry record.
Change in muscle volume
Time frame: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)
Not reported in this registry record.
Change in pennation angle (PA)
Time frame: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)
Not reported in this registry record.
Secondary measures
Change in eccentric strength
Time frame: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)
Eccentric hamstring strength of each limb will be assessed during the hamstring exercise.
Change in inertial measurement units (IMU)-based sprinting biomechanics
Time frame: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)
Sprinting biomechanics will be assessed using seven IMUs (sacrum, both thighs, both shanks, both feet). Lower extremity joint motions referenced to upright stance will be calculated throughout an on-field sprint and other football drills.
Change in countermovement jump (CMJ) performance
Time frame: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)
Not reported in this registry record.
Change in standing broad jump (SBJ) performance
Time frame: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)
Not reported in this registry record.
Change in change of direction (CoD) performance
Time frame: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)
Not reported in this registry record.
Change in range of motion (ROM) performance
Time frame: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)
Not reported in this registry record.
Change in hip flexion
Time frame: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)
Not reported in this registry record.
Change in anterior pelvic tilt
Time frame: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)
Not reported in this registry record.
Review the complete result tables and limitations in the official record.
Open official results ↗Research locations (1)
The overall study status and a local site’s status can differ. Confirm that location’s availability before traveling.
1 locations
University of Wisconsin - MadisonMadison, Wisconsin, United StatesRecruiting
Study team and timeline
- Lead sponsor
- University of Wisconsin, Madison
- Study start
- Aug 28, 2026 Actual
- Primary completion
- 2027-09 Estimated
- Study completion
- 2027-09 Estimated
- First posted
- Jul 21, 2026 Actual
- Last updated
- Nov 10, 2026 Actual
Official study contacts
Official study title
Comparison Between Eccentric Hamstring Strength Training and Sprint-Specific Training on Muscle Hypertrophy, Strength, Power, and Sprint Performance in Club Sport Collegiate Athletes
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Source: ClinicalTrials.gov API v2. Information is submitted by sponsors and investigators. NLM does not approve the safety or science of all listed studies. Registry disclaimer.
Retrieved: Nov 12, 2026 · Last registry update: Nov 10, 2026
