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RecruitingNCT07716319ClinicalTrials.gov record

Comparison Between Eccentric Hamstring Training and Sprint-Specific Training

Healthy Adult · Athlete · Exercise Training · Sport · Running · Ultrasound Imaging

THE QUICK READ

What this study involves

The registry says this study is recruiting. Individual locations may have different availability.

Study type
Interventional
Phase
Not applicable
Age range
18 years - 25 years
Sex eligible
All sexes
Healthy volunteers
Accepted
Participants
90 Estimated

These are starting points, not an eligibility decision. The research team must review the full requirements.

About the research

The purpose of this study is to compare the effects of an intensity-, volume-, and time under tension-matched eccentric hamstring exercise intervention with the Romanian deadlift (RDL) and the Nordic hamstring exercise (NHE) to a sprint-specific training program on hamstring muscle architecture, volume, sprint performance, strength, and power.

Participants will be assigned to complete one of the 3 hamstring interventions for 10 weeks.

Read the full description

Prior to the intervention, participants will undergo baseline testing which will include a) ultrasound imaging of the hamstrings muscles for measures of biceps femoris long head fascicle length, pennation angle, muscle thickness, anatomical cross-sectional area, and muscle volume b) passive and active ranges of motion, c) 3 repetition maximum (3RM) RDL strength, d) peak NHE force, e) countermovement jump height, f) broad jump distance, g) Pro Agility change of direction, and h) a 60 m sprint with sprint kinematics assessed via inertial measurement units.

Participants will be randomly assigned to either the RDL, NHE, or sprint training group. After randomization, each participant will undergo the intervention program based upon their group allocation.

Performance testing and imaging will be repeated mid-intervention, following the intervention, and after 2 weeks of deloading.

Who may be able to participate?

The list below is the sponsor’s full registry wording. It can include conditions, prior treatment, test results and other requirements. A match in search does not mean you qualify.

Inclusion Criteria:

  • Age 18-25 years
  • Actively participating in a club team
  • \>6 months experience with resistance training
  • Minimum of 1 year experience at the high school level in organized team sport
  • No history of hamstring injury within the last 6 months
  • No history of major lower extremity surgery (including back)
  • No acute musculoskeletal injury to the lower extremity
  • Not currently pregnant

Exclusion Criteria:

  • Unable to refrain from resistance training outside the study
  • Unable to make at least 80% of the training sessions
  • Hamstring injury in the last 6 months
  • History of major lower extremity surgery (including back)
  • Acute musculoskeletal injury to the lower extremity
  • Currently pregnant
Understand screening

Treatment, groups and participation

The registry may describe treatments and study duration without a complete visit calendar. Ask the study team for the exact schedule, procedures, risks, costs and alternatives. Keep your usual care plan unless your treating clinician tells you otherwise.

Assignment
Random assignment
Masking
Double masked
Romanian dead lift (RDL) group

The training intervention groups will undergo the same program with the only difference being the interventional hamstring exercise. The program will consist of a 2-week familiarization period followed by 8 weeks of progressive training. The RDL arm will perform RDL.

Other: RDL

Nordic hamstring exercise (NHE) group

The training intervention groups will undergo the same program with the only difference being the interventional hamstring exercise. The program will consist of a 2-week familiarization period followed by 8 weeks of progressive training. The NHE arm will performed NHE

Other: NHE

Sprint group

The training intervention groups will undergo the same program with the only difference being the interventional hamstring exercise. The program will consist of a 2-week familiarization period followed by 8 weeks of progressive training. The sprint training program will be performed twice per week with the first day of training focused on shorter distances to focus on acceleration and the second training day focused on maximal velocity. The relative efforts and distances for each training day will mimic a similar prescription to that of the resistance training program.

Other: Sprint testing

RDL OTHER

The RDL will be performed with a 6 second eccentric component with the athlete returning to the start position with a maximal concentric hip extension.

NHE OTHER

The NHE will be performed with a 6 second eccentric component.

Sprint testing OTHER

The sprint training program will be performed twice per week with the first day of training focused on shorter distances to focus on acceleration and the second training day focused on maximal velocity. The relative efforts and distances for each training day will mimic a similar prescription to that of the resistance training program.

Prepare your questions

What researchers are measuring

Outcome measures describe what is being studied. They are not proof that a treatment works.

Primary measures

Change in fascicle length (FL)

Time frame: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)

Not reported in this registry record.

Change in muscle cross-sectional area (CSA)

Time frame: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)

Not reported in this registry record.

Change in muscle volume

Time frame: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)

Not reported in this registry record.

Change in pennation angle (PA)

Time frame: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)

Not reported in this registry record.

Secondary measures

Change in eccentric strength

Time frame: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)

Eccentric hamstring strength of each limb will be assessed during the hamstring exercise.

Change in inertial measurement units (IMU)-based sprinting biomechanics

Time frame: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)

Sprinting biomechanics will be assessed using seven IMUs (sacrum, both thighs, both shanks, both feet). Lower extremity joint motions referenced to upright stance will be calculated throughout an on-field sprint and other football drills.

Change in countermovement jump (CMJ) performance

Time frame: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)

Not reported in this registry record.

Change in standing broad jump (SBJ) performance

Time frame: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)

Not reported in this registry record.

Change in change of direction (CoD) performance

Time frame: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)

Not reported in this registry record.

Change in range of motion (ROM) performance

Time frame: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)

Not reported in this registry record.

Change in hip flexion

Time frame: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)

Not reported in this registry record.

Change in anterior pelvic tilt

Time frame: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)

Not reported in this registry record.

No results are flagged as posted.

Review the complete result tables and limitations in the official record.

Open official results ↗

Research locations (1)

The overall study status and a local site’s status can differ. Confirm that location’s availability before traveling.

1 locations

University of Wisconsin - MadisonMadison, Wisconsin, United StatesRecruiting

Study team and timeline

Lead sponsor
University of Wisconsin, Madison
Study start
Aug 28, 2026 Actual
Primary completion
2027-09 Estimated
Study completion
2027-09 Estimated
First posted
Jul 21, 2026 Actual
Last updated
Nov 10, 2026 Actual

Official study contacts

Scott K Crawford, PhDCONTACTskcrawford2@wisc.edu608) 265-1308
Official study title

Comparison Between Eccentric Hamstring Strength Training and Sprint-Specific Training on Muscle Hypertrophy, Strength, Power, and Sprint Performance in Club Sport Collegiate Athletes

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Source: ClinicalTrials.gov API v2. Information is submitted by sponsors and investigators. NLM does not approve the safety or science of all listed studies. Registry disclaimer.

Retrieved: Nov 12, 2026 · Last registry update: Nov 10, 2026