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CompletedNCT07711431ClinicalTrials.gov record

Association Between Periodontal Disease and Chronic Neck Pain

Periodontal Disease · Chronic Neck Pain

THE QUICK READ

What this study involves

The registry does not currently label this study as recruiting. Ask about its status before planning a screening visit.

Study type
Observational
Phase
Not applicable / not listed
Age range
30 years - 55 years
Sex eligible
All sexes
Healthy volunteers
Accepted
Participants
138 Actual

These are starting points, not an eligibility decision. The research team must review the full requirements.

About the research

This study investigates whether there is an association between periodontal disease (gum disease) and chronic neck pain and related functional disability. Participants aged 30-55 years will be grouped based on their periodontal health status (healthy, gingivitis, or periodontitis). Neck pain intensity will be assessed using the Visual Analog Scale (VAS), and functional disability will be measured using the Neck Disability Index (NDI). The study aims to determine whether periodontal disease severity is linked to the severity of neck pain and disability, which may help clarify a potential connection between oral health and musculoskeletal health.

Read the full description

Periodontal disease is a chronic inflammatory condition affecting the tissues supporting the teeth, and has been increasingly linked to systemic inflammatory processes that may contribute to musculoskeletal pain conditions. Chronic non-specific neck pain is a common musculoskeletal complaint with a multifactorial etiology, and inflammatory mechanisms have been proposed as one potential contributing pathway.

This cross-sectional study aims to evaluate the association between periodontal disease status and chronic non-specific neck pain and related functional disability. Participants will undergo a periodontal examination, including assessment of gingival index, plaque index, bleeding on probing, probing depth, and radiographic bone loss, and will be classified into periodontal health categories according to the 2017 World Workshop classification of periodontal and peri-implant diseases and conditions.

Neck pain intensity and functional disability will be assessed using validated outcome measures. Associations between periodontal disease severity and neck pain/disability outcomes will be examined, along with potential confounding factors.

Findings from this study may contribute to a better understanding of the relationship between oral health and musculoskeletal health, and may inform future interdisciplinary approaches to patient assessment and care.

Who may be able to participate?

The list below is the sponsor’s full registry wording. It can include conditions, prior treatment, test results and other requirements. A match in search does not mean you qualify.

Inclusion Criteria:

  • Aged between 30 and 55 years
  • Willing to participate and provide written informed consent
  • Able to undergo periodontal examination and complete self-report questionnaires

Exclusion Criteria:

  • Neck pain attributable to a specific identifiable cause (e.g., trauma, cervical disc herniation, spinal deformity, tumor, fracture)
  • Systemic inflammatory or autoimmune disease
  • Neurological disease affecting the cervical region
  • Pregnancy
  • Regular use of analgesic or anti-inflammatory medication
  • Fewer than 20 remaining natural teeth
  • History of periodontal treatment within the past 6 months

Study population

Adults aged 30-55 years attending the Department of Periodontology, Faculty of Dentistry, Niğde Ömer Halisdemir University, who will be classified into three groups based on periodontal health status: clinically healthy periodontium, gingivitis, or periodontitis (Stage I-IV).

Understand screening

Treatment, groups and participation

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Assignment
Not reported
Masking
Not reported
Healthy

Participants with a clinically healthy periodontium, showing no clinical signs of gingival inflammation, attachment loss, or bone loss on periodontal examination.

Gingivitis

Participants diagnosed with gingivitis based on clinical periodontal examination, showing signs of gingival inflammation without attachment or bone loss.

Periodontitis

Participants diagnosed with periodontitis (Stage I, II, III, or IV) according to the 2017 World Workshop classification of periodontal and peri-implant diseases and conditions.

Prepare your questions

What researchers are measuring

Outcome measures describe what is being studied. They are not proof that a treatment works.

Primary measures

Neck Pain Intensity (Visual Analog Scale, VAS)

Time frame: Assessed at the time of study enrollment (baseline, single time point)

Neck pain intensity will be assessed using the Visual Analog Scale (VAS), a 10-cm horizontal line ranging from 0 (no pain) to 10 (worst imaginable pain). Participants will mark the point that best represents their current level of neck pain. Scores will be compared across periodontal health groups (healthy, gingivitis, periodontitis).

Neck-Related Functional Disability (Neck Disability Index, NDI)

Time frame: Assessed at the time of study enrollment (baseline, single time point)

Functional disability related to neck pain will be assessed using the Neck Disability Index (NDI), a validated 10-item self-report questionnaire evaluating the impact of neck pain on daily activities. Scores will be compared across periodontal health groups (healthy, gingivitis, periodontitis).

No results are flagged as posted.

Review the complete result tables and limitations in the official record.

Open official results ↗

Research locations (1)

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1 locations

Niğde Ömer Halisdemir University, Faculty of DentistryNiğde, Niğde Province, Turkey (Türkiye)Status unknown

Study team and timeline

Lead sponsor
Nigde Omer Halisdemir University
Study start
Jul 20, 2026 Actual
Primary completion
Sep 15, 2026 Actual
Study completion
Oct 15, 2026 Actual
First posted
Jul 17, 2026 Actual
Last updated
Nov 10, 2026 Actual

Official study contacts

No central contact is listed. Check the locations and the official record.

Official study title

Evaluation of the Association Between Periodontal Diseases and Chronic Non-Specific Neck Pain and Functional Disability: A Cross-Sectional Study

A HUMAN NEXT STEP

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Source: ClinicalTrials.gov API v2. Information is submitted by sponsors and investigators. NLM does not approve the safety or science of all listed studies. Registry disclaimer.

Retrieved: Nov 12, 2026 · Last registry update: Nov 10, 2026