Association Between Periodontal Disease and Chronic Neck Pain
Periodontal Disease · Chronic Neck Pain
What this study involves
The registry does not currently label this study as recruiting. Ask about its status before planning a screening visit.
- Study type
- Observational
- Phase
- Not applicable / not listed
- Age range
- 30 years - 55 years
- Sex eligible
- All sexes
- Healthy volunteers
- Accepted
- Participants
- 138 Actual
These are starting points, not an eligibility decision. The research team must review the full requirements.
About the research
This study investigates whether there is an association between periodontal disease (gum disease) and chronic neck pain and related functional disability. Participants aged 30-55 years will be grouped based on their periodontal health status (healthy, gingivitis, or periodontitis). Neck pain intensity will be assessed using the Visual Analog Scale (VAS), and functional disability will be measured using the Neck Disability Index (NDI). The study aims to determine whether periodontal disease severity is linked to the severity of neck pain and disability, which may help clarify a potential connection between oral health and musculoskeletal health.
Read the full description
Periodontal disease is a chronic inflammatory condition affecting the tissues supporting the teeth, and has been increasingly linked to systemic inflammatory processes that may contribute to musculoskeletal pain conditions. Chronic non-specific neck pain is a common musculoskeletal complaint with a multifactorial etiology, and inflammatory mechanisms have been proposed as one potential contributing pathway.
This cross-sectional study aims to evaluate the association between periodontal disease status and chronic non-specific neck pain and related functional disability. Participants will undergo a periodontal examination, including assessment of gingival index, plaque index, bleeding on probing, probing depth, and radiographic bone loss, and will be classified into periodontal health categories according to the 2017 World Workshop classification of periodontal and peri-implant diseases and conditions.
Neck pain intensity and functional disability will be assessed using validated outcome measures. Associations between periodontal disease severity and neck pain/disability outcomes will be examined, along with potential confounding factors.
Findings from this study may contribute to a better understanding of the relationship between oral health and musculoskeletal health, and may inform future interdisciplinary approaches to patient assessment and care.
Who may be able to participate?
The list below is the sponsor’s full registry wording. It can include conditions, prior treatment, test results and other requirements. A match in search does not mean you qualify.
Inclusion Criteria:
- Aged between 30 and 55 years
- Willing to participate and provide written informed consent
- Able to undergo periodontal examination and complete self-report questionnaires
Exclusion Criteria:
- Neck pain attributable to a specific identifiable cause (e.g., trauma, cervical disc herniation, spinal deformity, tumor, fracture)
- Systemic inflammatory or autoimmune disease
- Neurological disease affecting the cervical region
- Pregnancy
- Regular use of analgesic or anti-inflammatory medication
- Fewer than 20 remaining natural teeth
- History of periodontal treatment within the past 6 months
Study population
Adults aged 30-55 years attending the Department of Periodontology, Faculty of Dentistry, Niğde Ömer Halisdemir University, who will be classified into three groups based on periodontal health status: clinically healthy periodontium, gingivitis, or periodontitis (Stage I-IV).
Understand screeningTreatment, groups and participation
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- Assignment
- Not reported
- Masking
- Not reported
Healthy
Participants with a clinically healthy periodontium, showing no clinical signs of gingival inflammation, attachment loss, or bone loss on periodontal examination.
Gingivitis
Participants diagnosed with gingivitis based on clinical periodontal examination, showing signs of gingival inflammation without attachment or bone loss.
Periodontitis
Participants diagnosed with periodontitis (Stage I, II, III, or IV) according to the 2017 World Workshop classification of periodontal and peri-implant diseases and conditions.
What researchers are measuring
Outcome measures describe what is being studied. They are not proof that a treatment works.
Primary measures
Neck Pain Intensity (Visual Analog Scale, VAS)
Time frame: Assessed at the time of study enrollment (baseline, single time point)
Neck pain intensity will be assessed using the Visual Analog Scale (VAS), a 10-cm horizontal line ranging from 0 (no pain) to 10 (worst imaginable pain). Participants will mark the point that best represents their current level of neck pain. Scores will be compared across periodontal health groups (healthy, gingivitis, periodontitis).
Neck-Related Functional Disability (Neck Disability Index, NDI)
Time frame: Assessed at the time of study enrollment (baseline, single time point)
Functional disability related to neck pain will be assessed using the Neck Disability Index (NDI), a validated 10-item self-report questionnaire evaluating the impact of neck pain on daily activities. Scores will be compared across periodontal health groups (healthy, gingivitis, periodontitis).
Review the complete result tables and limitations in the official record.
Open official results ↗Research locations (1)
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1 locations
Niğde Ömer Halisdemir University, Faculty of DentistryNiğde, Niğde Province, Turkey (Türkiye)Status unknown
Study team and timeline
- Lead sponsor
- Nigde Omer Halisdemir University
- Study start
- Jul 20, 2026 Actual
- Primary completion
- Sep 15, 2026 Actual
- Study completion
- Oct 15, 2026 Actual
- First posted
- Jul 17, 2026 Actual
- Last updated
- Nov 10, 2026 Actual
Official study contacts
No central contact is listed. Check the locations and the official record.
Official study title
Evaluation of the Association Between Periodontal Diseases and Chronic Non-Specific Neck Pain and Functional Disability: A Cross-Sectional Study
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Source: ClinicalTrials.gov API v2. Information is submitted by sponsors and investigators. NLM does not approve the safety or science of all listed studies. Registry disclaimer.
Retrieved: Nov 12, 2026 · Last registry update: Nov 10, 2026
