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RecruitingNCT06820905ClinicalTrials.gov record

Hyperinflammation and Hyperferritinemia in Critically Ill Patients

Critical Illness · Sepsis · Hyperferritinemia · Hyperinflammatory Syndrome

THE QUICK READ

What this study involves

The registry says this study is recruiting. Individual locations may have different availability.

Study type
Observational
Phase
Not applicable / not listed
Age range
18 years - Not specified
Sex eligible
All sexes
Healthy volunteers
Not accepted
Participants
1962 Estimated

These are starting points, not an eligibility decision. The research team must review the full requirements.

About the research

Analysing trajectory of critically ill patients with signs of hyperinflammation

Who may be able to participate?

The list below is the sponsor’s full registry wording. It can include conditions, prior treatment, test results and other requirements. A match in search does not mean you qualify.

Inclusion Criteria:

  • critically ill patients
  • admission between 01.01.2020 and 31.12.2024 (5yrs)

Exclusion Criteria:

  • none

Study population

critically ill patients; mix-cases medical ICU population

Understand screening

Treatment, groups and participation

The registry may describe treatments and study duration without a complete visit calendar. Ask the study team for the exact schedule, procedures, risks, costs and alternatives. Keep your usual care plan unless your treating clinician tells you otherwise.

Assignment
Not reported
Masking
Not reported
critically ill patients

critically ill patients admitted to ICU between 01.01.2020 and 31.12.2024

Prepare your questions

What researchers are measuring

Outcome measures describe what is being studied. They are not proof that a treatment works.

Primary measures

hyperferritinemia

Time frame: 2025

trajectory of critically ill patients with significant hyperferritinemia and with regard to its dynamics; ferritin value cutt-off

Secondary measures

etiology and association of hyperferritinemia

Time frame: 2025

etiology and association of hyperferritinemia with infectioius a non-infectious diseases/conditions

mortality a morbidity

Time frame: 2025

mortality a morbidity of patients with significant hyperferritinemia

treatment strategy

Time frame: 2025

association of hyperferritinemia and treatment strategy

stratification

Time frame: 2025

patient stratification according to hyperferritinemia/hyperinflammation

No results are flagged as posted.

Review the complete result tables and limitations in the official record.

Open official results ↗

Research locations (1)

The overall study status and a local site’s status can differ. Confirm that location’s availability before traveling.

1 locations

Faculty of Medicine and Teaching Hospital, Charles UniversityPilsen, Czech Republic, CzechiaRecruiting

Study team and timeline

Lead sponsor
Charles University, Czech Republic
Study start
Oct 1, 2026 Actual
Primary completion
Dec 31, 2027 Estimated
Study completion
Jun 30, 2028 Estimated
First posted
Feb 11, 2025 Actual
Last updated
Nov 10, 2026 Actual

Official study contacts

Thomas Karvunidis, MD, PhDCONTACTkarvunidist@fnplzen.cz+420776160620
Official study title

Hyperinflammation and Hyperferritinemia in Critically Ill Patients: a Retrospective Observational Single-center Analysis

A HUMAN NEXT STEP

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Source: ClinicalTrials.gov API v2. Information is submitted by sponsors and investigators. NLM does not approve the safety or science of all listed studies. Registry disclaimer.

Retrieved: Nov 11, 2026 · Last registry update: Nov 10, 2026