Respiratory Muscle Functions With Balance and Gait in Stroke Patients
Chronic Stroke · Respiratory Muscles
What this study involves
The registry does not currently label this study as recruiting. Ask about its status before planning a screening visit.
- Study type
- Observational
- Phase
- Not applicable / not listed
- Age range
- 18 years - 85 years
- Sex eligible
- All sexes
- Healthy volunteers
- Not accepted
- Participants
- 27 Actual
These are starting points, not an eligibility decision. The research team must review the full requirements.
About the research
Stroke, which can occur due to many different causes and is one of the most common neurological conditions, is one of the main causes of disability worldwide. The most common disorders that occur after stroke are motor disorders. In addition, respiratory problems such as changes in breathing patterns and decreased ventilation function may accompany these patients. Respiratory problems are an important risk factor in the development of long-term mortality for both cardiovascular diseases and stroke. With all these changes, a serious decrease in patients' activity performance is observed. While the focus is on motor function losses in stroke rehabilitation, problems in pulmonary functions do not receive the necessary attention. In stroke rehabilitation, evaluating and treating patients from every perspective will further increase the effectiveness of the treatments applied.
Read the full description
According to WHO, stroke, also known as cerebrovascular accident, is a neurological condition that results in rapidly developing loss of brain function as a result of a problem in the blood supply to the brain. Stroke, which ranks third among the causes of death, is one of the leading causes of disability. Brain damage following stroke affects the central control of respiration, leading to various respiratory disorders. Dysfunction of the main respiratory muscle, the diaphragm, and particularly of the respiratory muscles on the paretic side of the body, is the most common and serious problem, causing asymmetric chest wall movements, changes in respiratory patterns, decreased lung volumes, and pulmonary complications. These changes in respiration cause further decreases in aerobic capacity, walking function, and the ability to perform daily living activities, especially in stroke patients who require an intensive rehabilitation program, and may increase the risk of pulmonary complications. At the same time, this situation may increase the risk of mortality by 2-6 times in stroke patients in the acute phase, prolong the average hospital stay, and worsen neurological dysfunctions. Therefore, evaluation of pulmonary functions and respiratory muscles before rehabilitation is very important to protect patients from possible accompanying pulmonary complications and to increase the effectiveness of the treatment.
Who may be able to participate?
The list below is the sponsor’s full registry wording. It can include conditions, prior treatment, test results and other requirements. A match in search does not mean you qualify.
Inclusion Criteria:
1. Having had a stroke for the first time
2. Being 18 years of age or older
3. Having an ischemic type of stroke
4. Having had a stroke for at least 6 months
5. Having a Modified Rankin Score of ≥3
6. Being able to communicate
7. Agreeing to participate in the study
Exclusion Criteria:
1. Hemispatial neglect
2. Having a psychiatric disease
3. Having any respiratory problems before the stroke
4. Having any orthopedic, neurological, cardiopulmonary disease that would constitute a contraindication for the protocols to be applied
Study population
Ischemic Stroke Patients
Understand screeningTreatment, groups and participation
The registry may describe treatments and study duration without a complete visit calendar. Ask the study team for the exact schedule, procedures, risks, costs and alternatives. Keep your usual care plan unless your treating clinician tells you otherwise.
- Assignment
- Not reported
- Masking
- Not reported
What researchers are measuring
Outcome measures describe what is being studied. They are not proof that a treatment works.
Primary measures
Respiratory Function Tests
Time frame: 1 day (It will be performed one time.)
These are tests used in combination with the clinic to evaluate and grade damage and abnormalities in respiratory system functions. Spirometric measurement reflects the time, volume and flow values measured during normal breathing, forced inspiration, forced expiration, deep and rapid breathing for a certain period of time. The test is evaluated by comparing the basal values obtained by creating gender, height, weight and age groups in healthy people in the community where the measurement is made. Lung functions physiologically consist of four volumes. Expiratory reserve volume (ERV), inspiratory reserve volume (IRV), residual volume (RV) and tidal volume (VT). The sum of the four volumes gives the total lung capacity (TLC).
Secondary measures
6-Minute Walk Test
Time frame: 1 day (It will be performed one time.)
The 6MWT is defined as a submaximal test that can be easily applied to healthy or sick individuals, and is evaluated as an indicator of exercise capacity and walking capacity, as well as many cardiovascular diseases. The 6MWT is referred to as the "Gold Standard" test of walking capacity.
Berg Balance Scale
Time frame: 1 day (It will be performed one time.)
A scale consisting of 14 tests that measure the ability to maintain balance during different positions, postural changes and movement. The assessment is based on the person's ability to perform each test independently and/or for a certain time or distance. The rating is made between 0 and 4 points (0: cannot perform, 4: normal performance). The total score varies between 0 (dependent) and 56 (independent).
Review the complete result tables and limitations in the official record.
Open official results ↗Research locations (1)
The overall study status and a local site’s status can differ. Confirm that location’s availability before traveling.
1 locations
Beykent ÜniversityIstanbul, Büyükçekmece, Turkey (Türkiye)Status unknown
Study team and timeline
- Lead sponsor
- Saglik Bilimleri Universitesi
- Study start
- Dec 28, 2024 Actual
- Primary completion
- Mar 2, 2025 Actual
- Study completion
- Apr 2, 2025 Actual
- First posted
- Jan 6, 2025 Actual
- Last updated
- Nov 9, 2026 Actual
Official study contacts
No central contact is listed. Check the locations and the official record.
Official study title
Relationship of Respiratory Muscle Functions With Balance and Gait in Chronic Ischemic Stroke Patients
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Source: ClinicalTrials.gov API v2. Information is submitted by sponsors and investigators. NLM does not approve the safety or science of all listed studies. Registry disclaimer.
Retrieved: Nov 12, 2026 · Last registry update: Nov 9, 2026