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A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

Crohn's Disease

Pregúntale a WCR sobre este estudio Registro oficial ↗
LO ESENCIAL

De qué trata este estudio

El registro indica que este estudio recluta participantes. La disponibilidad puede variar por centro.

Tipo de estudio
De intervención
Fase
Fase 3
Rango de edad
16 años - 80 años
Sexo admitido
Todos los sexos
Voluntarios sanos
No aceptados
Participantes
1200 Estimado

Estos son puntos de partida, no una decisión de elegibilidad. El equipo debe revisar todos los requisitos.

Las explicaciones y la navegación están en español. Los textos proporcionados por el registro, incluidos títulos, resúmenes y criterios, se conservan en su idioma original. Puedes pedir orientación en español a WCR.

Acerca de la investigación

The purpose of this protocol is to evaluate the efficacy and safety of tulisokibart in participants with moderately to severely active Crohn's disease. Study 1's primary hypotheses are that at least 1 tulisokibart dose level is superior to placebo in the proportion of participants achieving clinical remission per Crohn's Disease Activity Index score (\<150, US/FDA) or per stool frequency and abdominal pain score (EU/EMA) and in the proportion of participants achieving endoscopic response at Week 52 (US/FDA and EU/EMA), and that at least 1 tulisokibart dose level is superior to placebo in the proportion of participants achieving clinical remission per Crohn's Disease Activity Index score (\<150, US/FDA) or per stool frequency and abdominal pain score (EU/EMA) and in the proportion of participants achieving endoscopic response at Week 12 (US/FDA and EU/EMA). Study 2's primary hypothesis is that at least 1 tulisokibart dose level is superior to placebo in the proportion of participants achieving clinical remission per Crohn's Disease Activity Index score (\<150, US/FDA) or stool frequency and abdominal pain score (EU/EMA) and in the proportion of participants achieving endoscopic response at Week 12 (US/FDA and EU/EMA).

Leer la descripción completa

The protocol consists of 2 studies. Study 1 includes induction and maintenance treatment, and Study 2 includes only induction treatment. Each study has its own hypotheses and outcome measures that will be assessed independently.

¿Quién podría participar?

La lista siguiente contiene el texto del patrocinador. Puede incluir condiciones, tratamientos previos, resultados de pruebas y otros requisitos. Aparecer en tu búsqueda no significa que califiques.

The main inclusion and exclusion criteria include but are not limited to the following:

Inclusion Criteria:

  • Has had a diagnosis of Crohn's disease (CD) at least 3 months before study.
  • Has moderately to severely active CD.
  • Demonstrated inadequate response, loss of response, or intolerance to one or more of the following categories of drugs: oral locally acting steroids, systemic steroids, immunomodulators, biologic and/or small molecule advanced therapies.
  • Adolescent participants ≥16 and \<18 years of age can participate if approved by the country or regulatory/health authority.

Exclusion Criteria:

  • Has diagnosis of ulcerative colitis (UC) or indeterminate colitis.
  • Has CD isolated to the stomach, duodenum, jejunum, or perianal region, without colonic and/or ileal involvement.
  • Currently has any of the following complications of CD: suspected or diagnosed with intra-abdominal or perianal abscess, known symptomatic stricture or colonic stenosis not passable in endoscopy, fulminant colitis, toxic megacolon, or any other manifestation that might require surgery while enrolled in the study.
  • Has current stoma or need for colostomy or ileostomy.
  • Is missing \>2 segments of the following 5 segments: terminal ileum, right colon, transverse colon, sigmoid and left colon, and rectum.
  • Has been diagnosed with short gut or short bowel syndrome, or any other uncontrolled chronic diarrhea besides CD.
  • Has surgical bowel resection within 3 months of study.
  • Has prior or current gastrointestinal dysplasia.
  • Has chronic infection requiring ongoing antimicrobial treatment.
  • Has a history of cancer (except fully treated non-melanoma skin cell cancers or cervical carcinoma in situ after complete surgical removal) and is disease free for \<5 years.
  • Is infected with Hepatitis B virus (HBV), Hepatitis C virus (HCV), or human immunodeficiency virus (HIV).
  • Has active tuberculosis.
  • Has confirmed or suspected coronavirus disease of 2019 (COVID-19) infection.
  • Prior exposure to tulisokibart (MK-7240, PRA023) or another anti-tumor necrosis factor-like cytokine 1A (TL1A) antibody (Ab).
Entiende la evaluación inicial

Tratamiento, grupos y participación

El registro puede describir tratamientos y duración sin incluir un calendario completo. Pide al equipo las visitas, procedimientos, riesgos, costos y alternativas. Mantén tu atención habitual salvo que tu médico te indique un cambio.

Asignación
Asignación al azar
Enmascaramiento
Enmascaramiento cuádruple
Study 1: High Dose Induction, High Dose Maintenance

Participants receive high dose intravenous (IV) tulisokibart, followed by a high dose subcutaneous (SC) tulisokibart regimen.

Drug: IV Tulisokibart · Drug: SC Tulisokibart

Study 1: High Dose Induction, Low Dose Maintenance

Participants receive high dose IV tulisokibart, followed by a low dose SC tulisokibart regimen.

Drug: IV Tulisokibart · Drug: SC Tulisokibart · Other: SC Placebo

Study 1: Low Dose Induction, Low Dose Maintenance

Participants receive low dose IV tulisokibart, followed by a low dose SC tulisokibart regimen.

Drug: IV Tulisokibart · Drug: SC Tulisokibart · Other: SC Placebo

Study 1: Placebo

Participants receive IV placebo, followed by an SC placebo regimen.

Drug: IV Tulisokibart · Other: IV Placebo · Other: SC Placebo

Study 1: High Dose Extension

Participants receive a high dose SC tulisokibart regimen. Participants may continue in this arm after completing participation in their original arm, if they meet protocol-specific prerequisites.

Drug: SC Tulisokibart

Study 1: Low Dose Extension

Participants receive a low dose SC tulisokibart and placebo regimen. Participants may continue in this arm after completing participation in their original arm, if they meet protocol-specific prerequisites.

Drug: SC Tulisokibart · Other: SC Placebo

Study 2: High Dose Induction

Participants receive high dose IV tulisokibart.

Drug: IV Tulisokibart

Study 2: Low Dose Induction

Participants receive low dose IV tulisokibart.

Drug: IV Tulisokibart · Other: SC Placebo

Study 2: Placebo

Participants receive IV placebo.

Drug: IV Tulisokibart · Other: IV Placebo · Other: SC Placebo

Study 2: High Dose Extension

Participants receive a high dose SC tulisokibart regimen. Participants may continue in this arm only after completing participation in their original arm, if they meet protocol-specific prerequisites.

Drug: SC Tulisokibart

Study 2: Low Dose Extension

Participants receive a low dose SC tulisokibart regimen. Participants may continue in this arm only after completing participation in their original arm, if they meet protocol-specific prerequisites.

Drug: SC Tulisokibart

IV Tulisokibart DRUG

Humanized monoclonal antibody that binds human tumor necrosis factor-like cytokine 1A (TL1A), administered intravenously

SC Tulisokibart DRUG

Humanized monoclonal antibody that binds human TL1A, administered subcutaneously

IV Placebo OTHER

Placebo matching IV tulisokibart

SC Placebo OTHER

Placebo matching SC tulisokibart

Prepara tus preguntas

Qué evalúan los investigadores

Estas medidas indican qué se estudia. No prueban que un tratamiento funcione.

Medidas principales

Study 1 [US/FDA Only]: Percentage of Participants Achieving Clinical Remission per Crohn's Disease Activity Index (CDAI) Score at Week 52

Plazo: Week 52

The percentage of participants achieving clinical remission, as defined by CDAI score \<150 for Study 1 will be presented.

Study 1 [EU/EMA Only]: Percentage of Participants Achieving Clinical Remission per Stool Frequency and Abdominal Pain Score at Week 52

Plazo: Week 52

The percentage of participants achieving clinical remission per stool frequency/abdominal pain score (SF/APS), as defined by average daily SF ≤2.8 and average daily APS ≤1.0 and both not greater than baseline for Study 1 will be presented.

Study 1: Percentage of Participants Achieving Endoscopic Response at Week 52

Plazo: Week 52

The percentage of participants achieving endoscopic response, as defined by a ≥50% decrease in Simplified endoscopic score for Crohn's disease (SES-CD) from baseline for Study 1 will be presented.

Study 1 [US/FDA Only]: Percentage of Participants Achieving Clinical Remission per CDAI Score at Week 12

Plazo: Week 12

The percentage of participants achieving clinical remission, as defined by CDAI score \<150 for Study 1 will be presented.

Study 1 [EU/EMA Only]: Percentage of Participants Achieving Clinical Remission per Stool Frequency and Abdominal Pain Score at Week 12

Plazo: Week 12

The percentage of participants achieving clinical remission per SF/APS, as defined by average daily SF ≤2.8 and average daily APS ≤1.0 and both not greater than baseline for Study 1 will be presented.

Study 1: Percentage of Participants Achieving Endoscopic Response at Week 12

Plazo: Week 12

The percentage of participants achieving endoscopic response, as defined by a ≥50% decrease in SES-CD from baseline for Study 1 will be presented.

Study 2 [US/FDA Only]: Percentage of Participants Achieving Clinical Remission per CDAI Score at Week 12

Plazo: Week 12

The percentage of participants achieving clinical remission, as defined by CDAI score \<150 for Study 2 will be presented.

Study 2 [EU/EMA Only]: Percentage of Participants Achieving Clinical Remission per Stool Frequency and Abdominal Pain Score at Week 12

Plazo: Week 12

The percentage of participants achieving clinical remission per SF/APS, as defined by average daily SF ≤2.8 and average daily APS ≤1.0 and both not greater than baseline for Study 2 will be presented.

Study 2: Percentage of Participants Achieving Endoscopic Response at Week 12

Plazo: Week 12

The percentage of participants achieving endoscopic response, as defined by a ≥50% decrease in SES-CD from baseline for Study 2 will be presented.

Medidas secundarias

Study 1: Number of Participants Who Experienced an Adverse Event (AE)

Plazo: Up to approximately 52 weeks

An AE is any untoward medical occurrence in a clinical study participant, temporally associated with the use of study intervention, whether or not considered related to the study intervention. An AE can therefore be any unfavorable and unintended sign (including an abnormal laboratory finding), symptom, or disease (new or exacerbated) temporally associated with the use of a study intervention. The number of participants who experience an AE for Study 1 will be presented.

Study 1: Number of Participants Who Discontinue Study Intervention due to an AE

Plazo: Up to approximately 52 weeks

An AE is any untoward medical occurrence in a clinical study participant, temporally associated with the use of study intervention, whether or not considered related to the study intervention. An AE can therefore be any unfavorable and unintended sign (including an abnormal laboratory finding), symptom, or disease (new or exacerbated) temporally associated with the use of a study intervention. The number of participants who discontinue study intervention due to an AE for Study 1 will be presented.

Study 1 [US/FDA Only]: Percentage of Participants Achieving Clinical Remission per Stool Frequency and Abdominal Pain Score at Week 12

Plazo: Week 12

The percentage of participants achieving clinical remission per SF/APS, as defined by average daily SF ≤2.8 and average daily APS ≤1.0 and both not greater than baseline for Study 1 will be presented.

Study 1 [EU/EMA Only]: Percentage of Participants Achieving Clinical Remission per CDAI Score at Week 12

Plazo: Week 12

The percentage of participants achieving clinical remission, as defined by CDAI score \<150 for Study 1 will be presented.

Study 1: Percentage of Participants With Clinical Response per CDAI Score (Decrease From Baseline of ≥100 Points) at Week 12

Plazo: Week 12

The percentage of participants achieving clinical response, defined as decrease from baseline of ≥100 points in CDAI for Study 1 will be presented.

Study 1: Mean Change From Baseline in Functional Assessment of Chronic Illness Therapy - Fatigue (FACIT-Fatigue) Score at Week 12

Plazo: Baseline and Week 12

The FACIT-Fatigue is a 13-item measure that assesses self-reported fatigue and its impact upon daily activities and function, scored on a 0 to 52-point scale, with lower scores indicating greater fatigue. The mean change from baseline in FACIT-Fatigue score for Study 1 will be presented.

Study 1: Percentage of Participants Achieving Endoscopic Remission at Week 12

Plazo: Week 12

The percentage of participants achieving endoscopic remission, as defined by SES-CD ≤4 and at least 2-point reduction from baseline and no subscore \>1 in any individual variable for Study 1 will be presented. SES-CD evaluates 4 endoscopic variables (ulcer size, ulcerated surface, affected surface, and narrowing), each on a scale from 0 to 3, in 5 segments assessed during ileocolonoscopy (ileum, right colon, transverse colon, left colon/sigmoid, and rectum). The total score is the sum of the 4 endoscopic variable scores and ranges from 0 to 56, where higher scores indicate more severe disease.

Study 1 and 2: Percentage of Participants in Diagnostic Assay Positive (Dx+) Subpopulation Achieving Clinical Remission per CDAI Score at Week 12

Plazo: Week 12

Dx+ participants are those who meet protocol-specific diagnostic assay criteria during screening. The percentage of Dx+ participants achieving clinical remission, as defined by CDAI score \<150 for Study 1 and Study 2 will be presented.

Study 1 and 2: Percentage of Participants in Dx+ Subpopulation Achieving Endoscopic Response at Week 12

Plazo: Week 12

Dx+ participants are those who meet protocol-specific diagnostic assay criteria during screening. The percentage of Dx+ participants achieving endoscopic response, as defined by a ≥50% decrease in simplified endoscopic score for Crohn's disease (CD) from baseline for Study 1 and Study 2 will be presented.

Study 1: Percentage of Participants With Clinical Response (Decrease From Baseline at Least 100 Points) or Clinical Remission (<150) per CDAI Score at Week 6

Plazo: Week 6

The percentage of participants achieving clinical response (defined as decrease from baseline of ≥100 points in CDAI) or clinical remission (defined as CDAI \<150) for Study 1 will be presented.

Study 1 [US/FDA Only]: Percentage of Participants Achieving Clinical Remission per Stool Frequency and Abdominal Pain Score at Week 52

Plazo: Week 52

The percentage of participants achieving clinical remission per SF/APS, as defined by average daily SF ≤2.8 and average daily APS ≤1.0 and both not greater than baseline for Study 1 will be presented.

Study 1 [EU/EMA Only]: Percentage of Participants Achieving Clinical Remission per CDAI Score at Week 52

Plazo: Week 52

The percentage of participants achieving clinical remission, as defined by CDAI score \<150 for Study 1 will be presented.

Study 1: Percentage of Participants With Clinical Response per CDAI Score (Decreased From Baseline of ≥100 Points) at Week 52

Plazo: Week 52

The percentage of participants achieving clinical response, defined as decrease from baseline of ≥100 points in CDAI for Study 1 will be presented.

Study 1: Percentage of Participants Achieving Endoscopic Remission at Week 52

Plazo: Week 52

The percentage of participants achieving endoscopic remission, as defined by SES-CD ≤4 and at least 2-point reduction from baseline and no subscore \>1 in any individual variable for Study 1 will be presented. SES-CD evaluates 4 endoscopic variables (ulcer size, ulcerated surface, affected surface, and narrowing), each on a scale from 0 to 3, in 5 segments assessed during ileocolonoscopy (ileum, right colon, transverse colon, left colon/sigmoid, and rectum). The total score is the sum of the 4 endoscopic variable scores and ranges from 0 to 56, where higher scores indicate more severe disease.

Study 1: Percentage of Participants Achieving Sustained Clinical Remission per CDAI at Both Week 12 and Week 52

Plazo: Week 12 and Week 52

The percentage of participants achieving sustained clinical remission, as defined by CDAI score \<150 for Study 1 will be presented.

Study 1 [US/FDA Only]: Percentage of Participants Achieving Corticosteroid-Free Clinical Remission per CDAI Score at Week 52

Plazo: Week 52

The percentage of participants who are in clinical remission as defined by CDAI score \<150 and without corticosteroid use for CD at least 90 days prior to that assessment for Study 1 will be presented.

Study 1 [EU/EMA Only]: Percentage of Participants Achieving Corticosteroid-Free Clinical Remission per Stool Frequency and Abdominal Pain Score at Week 52

Plazo: Week 52

The percentage of participants who are in clinical remission per SF/APS, as defined by average daily SF ≤2.8 and average daily APS ≤1.0 and both not greater than baseline and without corticosteroid use for CD at least 90 days prior to that assessment for Study 1 will be presented.

Study 1: Percentage of Participants Achieving Clinical Remission per Stool Frequency, Abdominal Pain Score, and Endoscopic Remission at Week 52

Plazo: Week 52

The percentage of participants achieving clinical remission per SF/APS, as defined by average daily SF ≤2.8 and average daily APS ≤1.0 and both not greater than baseline, and achieving endoscopic remission, as defined by SES-CD ≤4 and at least 2-point reduction from baseline and no subscore \>1 in any individual variable for Study 1 will be presented.

Study 1: Percentage of Participants Achieving Clinical Remission per CDAI Score and Endoscopic Remission at Week 52

Plazo: Week 52

The percentage of participants achieving clinical remission as defined by CDAI score \<150, and achieving endoscopic remission, as defined by SES-CD ≤4 and at least 2-point reduction from baseline and no subscore \>1 in any individual variable for Study 1 will be presented.

Study 1: Mean Change From Baseline in FACIT-Fatigue Score at Week 52

Plazo: Baseline and Week 52

The FACIT-Fatigue is a 13-item measure that assesses self-reported fatigue and its impact upon daily activities and function, scored on a 0 to 52-point scale, with lower scores indicating greater. The mean change from baseline in FACIT-Fatigue score for Study 1 will be presented.

Study 1 [EU/EMA Only]: Mean Change From Baseline in Inflammatory Bowel Disease Questionnaire (IBDQ) Score at Week 52

Plazo: Baseline and Week 52

The IBDQ measures health related quality of life in participants with inflammatory bowel disease. It consists of 32 questions each with a graded response of 1 (worst) to 7 (best). The score ranges between 32 to 224, with higher scores indicating a better quality of life. The mean change from baseline in IBDQ score for Study 1 will be presented.

Study 1: Percentage of Participants With Ulcer-Free Endoscopy at Week 52

Plazo: Week 52

The percentage of participants achieving ulcer-free endoscopy (mucosal healing), as defined by SES-CD ulcerated surface subscore of 0 in participants with SES-CD ulcerated surface subscore ≥1 at baseline for Study 1 will be presented.

Study 2: Number of Participants Who Experienced an AE

Plazo: Up to approximately 12 weeks

An AE is any untoward medical occurrence in a clinical study participant, temporally associated with the use of study intervention, whether or not considered related to the study intervention. An AE can therefore be any unfavorable and unintended sign (including an abnormal laboratory finding), symptom, or disease (new or exacerbated) temporally associated with the use of a study intervention. The number of participants who experience an AE for Study 2 will be presented.

Study 2: Number of Participants Who Discontinue Study Intervention due to an AE

Plazo: Up to approximately 12 weeks

An AE is any untoward medical occurrence in a clinical study participant, temporally associated with the use of study intervention, whether or not considered related to the study intervention. An AE can therefore be any unfavorable and unintended sign (including an abnormal laboratory finding), symptom, or disease (new or exacerbated) temporally associated with the use of a study intervention. The number of participants who discontinue study intervention due to an AE for Study 2 will be presented.

Study 2 [US/FDA Only]: Percentage of Participants Achieving Clinical Remission per Stool Frequency and Abdominal Pain Score at Week 12

Plazo: Week 12

The percentage of participants achieving clinical remission per SF/APS, as defined by average daily SF ≤2.8 and average daily APS ≤1.0 and both not greater than baseline for Study 2 will be presented.

Study 2 [EU/EMA Only]: Percentage of Participants Achieving Clinical Remission per CDAI Score at Week 12

Plazo: Week 12

The percentage of participants achieving clinical remission, as defined by CDAI score \<150 for Study 2 will be presented.

Study 2: Percentage of Participants With Clinical Response per CDAI Score (Decreased From Baseline of ≥100 Points) at Week 12

Plazo: Week 12

The percentage of participants achieving clinical response, defined as decrease from baseline of ≥100 points in CDAI for Study 2 will be presented.

Study 2: Mean Change From Baseline in FACIT-Fatigue Score at Week 12

Plazo: Baseline and Week 12

The FACIT-Fatigue is a 13-item measure that assesses self-reported fatigue and its impact upon daily activities and function, scored on a 0 to 52-point scale, with lower scores indicating greater. The mean change from baseline in FACIT-Fatigue score for Study 2 will be presented.

Study 2: Percentage of Participants Achieving Endoscopic Remission at Week 12

Plazo: Week 12

The percentage of participants achieving endoscopic remission, as defined by SES-CD ≤4 and at least 2-point reduction from baseline and no subscore \>1 in any individual variable for Study 2 will be presented. SES-CD evaluates 4 endoscopic variables (ulcer size, ulcerated surface, affected surface, and narrowing), each on a scale from 0 to 3, in 5 segments assessed during ileocolonoscopy (ileum, right colon, transverse colon, left colon/sigmoid, and rectum). The total score is the sum of the 4 endoscopic variable scores and ranges from 0 to 56, where higher scores indicate more severe disease.

Study 2 [EU/EMA Only]: Mean Change From Baseline in IBDQ Score at Week 12

Plazo: Baseline and Week 12

The IBDQ measures health related quality of life in participants with inflammatory bowel disease. It consists of 32 questions each with a graded response of 1 (worst) to 7 (best). The score ranges between 32 to 224, with higher scores indicating a better quality of life. The mean change from baseline in IBDQ score for Study 2 will be presented.

Study 2: Percentage of Participants With Clinical Response (Decreased From Baseline of ≥100 Points) or Clinical Remission (<150) per CDAI Score at Week 6

Plazo: Week 6

The percentage of participants achieving clinical response (defined as decrease from baseline of ≥100 points in CDAI) or clinical remission (defined as CDAI \<150) for Study 2 will be presented.

Study 2: Percentage of Participants With Ulcer-Free Endoscopy at Week 12

Plazo: Week 12

The percentage of participants achieving ulcer-free endoscopy (mucosal healing), as defined by SES-CD ulcerated surface subscore of 0 in participants with SES-CD ulcerated surface subscore ≥1 at baseline for Study 2 will be presented.

El registro no indica resultados publicados.

Revisa las tablas completas y sus limitaciones en el registro oficial.

Abrir resultados oficiales ↗

Centros de investigación (499)

El estado general puede diferir del estado de un centro. Confirma la disponibilidad antes de trasladarte.

499 centros

Digestive Health Specialists ( Site 5064)Dothan, Alabama, United StatesCompletado
Arizona Arthritis & Rheumatology Research, PC ( Site 5094)Phoenix, Arizona, United StatesCompletado
GI Alliance - Sun City ( Site 5118)Sun City, Arizona, United StatesReclutando
University of Arizona Clinical and Translational Sciences Research Center ( Site 5111)Tucson, Arizona, United StatesReclutando
University of Arkansas for Medical Sciences ( Site 5147)Little Rock, Arkansas, United StatesReclutando
Clinnova Research ( Site 5110)Anaheim, California, United StatesReclutando
Southern California Research Center ( Site 5044)Coronado, California, United StatesReclutando
Om Research LLC ( Site 5038)Lancaster, California, United StatesReclutando
Cedars Sinai Medical Center ( Site 5080)Los Angeles, California, United StatesReclutando
UCLA Clinical & Translational Research Center (CTRC) ( Site 5116)Los Angeles, California, United StatesReclutando
University of California, Irvine (UCI) Health - UC Irvine Medical Center ( Site 5128)Orange, California, United StatesReclutando
Om Research LLC ( Site 5045)Oxnard, California, United StatesReclutando
Clinical Applications Laboratories ( Site 5123)San Diego, California, United StatesReclutando
Amicis Research Center ( Site 5055)Valencia, California, United StatesCompletado
University of Colorado Anschutz Medical Campus-Division of Gastroenterology and Hepatology ( Site 5026)Aurora, Colorado, United StatesReclutando
Peak Gastroenterology Associates ( Site 5023)Colorado Springs, Colorado, United StatesReclutando
South Denver Gastroenterology, PC ( Site 5132)Englewood, Colorado, United StatesReclutando
Rocky Mountain Gastroenterology ( Site 5082)Lakewood, Colorado, United StatesReclutando
Medical Research Center of Connecticut ( Site 5005)Hamden, Connecticut, United StatesCompletado
Yale University School of Medicine-Digestive Disease ( Site 5019)New Haven, Connecticut, United StatesReclutando
Emerson Clinical Research Institute ( Site 5051)Washington D.C., District of Columbia, United StatesReclutando
Gastroenterology Consultants of Clearwater ( Site 5052)Clearwater, Florida, United StatesActivo, sin reclutamiento
Covenant Metabolic Specialists, LLC ( Site 5150)Fort Myers, Florida, United StatesReclutando
Nature Coast Clinical Research - Inverness ( Site 5042)Inverness, Florida, United StatesReclutando
Atlantic Medical Research ( Site 5073)Margate, Florida, United StatesActivo, sin reclutamiento
Sanchez Clinical Research ( Site 5144)Miami, Florida, United StatesReclutando
AdventHealth Orlando ( Site 5131)Orlando, Florida, United StatesReclutando
Endoscopic Research Inc ( Site 5061)Orlando, Florida, United StatesReclutando
Orlando Health-Digestive Health Institute ( Site 5010)Orlando, Florida, United StatesCompletado
USF Health Carol and Frank Morsani Center for Advanced Healthcare ( Site 5039)Tampa, Florida, United StatesReclutando
Covenant Metabolic Specialists, LLC ( Site 5143)University Park, Florida, United StatesReclutando
Morehouse School Of Medicine ( Site 5071)Atlanta, Georgia, United StatesReclutando
Atlanta Center for Gastroenterology ( Site 5035)Decatur, Georgia, United StatesCompletado
Gastroenterology Associates of Central Georgia ( Site 5048)Macon, Georgia, United StatesReclutando
Eagle Clinical Research ( Site 5089)Chicago, Illinois, United StatesCompletado
University of Chicago Medical Center ( Site 5066)Chicago, Illinois, United StatesReclutando
Endeavor Health ( Site 5018)Evanston, Illinois, United StatesReclutando
GI ALLIANCE - GURNEE ( Site 5003)Gurnee, Illinois, United StatesReclutando
Indiana University Health University Hospital ( Site 5022)Indianapolis, Indiana, United StatesReclutando
Iowa Digestive Disease Center ( Site 5007)Clive, Iowa, United StatesReclutando
University of Kansas Medical Center ( Site 5091)Kansas City, Kansas, United StatesReclutando
Cotton O'Neil Digestive Health Center ( Site 5033)Topeka, Kansas, United StatesReclutando
University of Louisville Hospital ( Site 5120)Louisville, Kentucky, United StatesReclutando
Southern Clinical Research ( Site 5095)Zachary, Louisiana, United StatesCompletado
Walter Reed National Military Medical Center ( Site 5006)Bethesda, Maryland, United StatesReclutando
Massachusetts General Hospital-Crohn's and Colitis Center ( Site 5037)Boston, Massachusetts, United StatesReclutando
University of Michigan ( Site 5060)Ann Arbor, Michigan, United StatesReclutando
Clinical Research Institute of Michigan, LLC ( Site 5002)Clinton Township, Michigan, United StatesReclutando
Mayo Clinic in Rochester, Minnesota ( Site 5024)Rochester, Minnesota, United StatesReclutando
Mid-America GI Clinical Research ( Site 5130)Kansas City, Missouri, United StatesReclutando
BVL Research - Kansas ( Site 5099)Liberty, Missouri, United StatesReclutando
Washington University School of Medicine ( Site 5058)St Louis, Missouri, United StatesReclutando
HMH Justice Marie Garibaldi Medical Plaza ( Site 5072)Hackensack, New Jersey, United StatesReclutando
Northwell Health Physician Partners Center for Advanced IBD Care ( Site 5017)Great Neck, New York, United StatesReclutando
Circuit Clinical /Crystal Run Healthcare LLP ( Site 5050)Middletown, New York, United StatesActivo, sin reclutamiento
NYU Langone Health - Inflammatory Bowel Disease Center (IBD) ( Site 5078)New York, New York, United StatesReclutando
Weill Cornell Medical College, New-York Presbyterian Hospital ( Site 5079)New York, New York, United StatesReclutando
New York Gastroenterology Associates ( Site 5013)New York, New York, United StatesReclutando
Northwell Mather Hospital ( Site 5138)Port Jefferson, New York, United StatesReclutando
University of North Carolina Medical Center ( Site 5034)Chapel Hill, North Carolina, United StatesReclutando
Atrium Health Gastroenterology MMP ( Site 5105)Charlotte, North Carolina, United StatesReclutando
Javara - Tryon Medical Partners ( Site 5046)Charlotte, North Carolina, United StatesCompletado
Great Lakes Gastroenterology Research, LLC ( Site 5016)Mentor, Ohio, United StatesReclutando
Digestive Disease Specialists Inc. ( Site 5117)Oklahoma City, Oklahoma, United StatesReclutando
Penn State University Milton S. Hershey Medical Center ( Site 5102)Hershey, Pennsylvania, United StatesReclutando
Thomas Jefferson University Hospital ( Site 5133)Philadelphia, Pennsylvania, United StatesReclutando
Frontier Clinical Research, LLC ( Site 5098)Uniontown, Pennsylvania, United StatesReclutando
University Gastroenterology - Providence - West River Street ( Site 5057)Providence, Rhode Island, United StatesReclutando
Sanford USD Medical Center ( Site 5129)Sioux Falls, South Dakota, United StatesReclutando
Vanderbilt Inflammatory Bowel Disease Clinic ( Site 5049)Nashville, Tennessee, United StatesReclutando
Quality Medical Research ( Site 5114)Nashville, Tennessee, United StatesReclutando
Baylor University Medical Center ( Site 5031)Dallas, Texas, United StatesReclutando
GI Alliance - Dallas - Gaston Avenue ( Site 5054)Dallas, Texas, United StatesCompletado
Epic Medical Research - Mesquite ( Site 5153)Denton, Texas, United StatesReclutando
Baylor College of Medicine Medical Center ( Site 5020)Houston, Texas, United StatesReclutando
Michael E. DeBakey VA Medical Center ( Site 5086)Houston, Texas, United StatesReclutando
GI Alliance - Lubbock ( Site 5012)Lubbock, Texas, United StatesCompletado
Caprock Gastro Research ( Site 5077)Lubbock, Texas, United StatesReclutando
GI Alliance: Mansfield ( Site 5015)Mansfield, Texas, United StatesActivo, sin reclutamiento
Southern Star Research Institute ( Site 5000)San Antonio, Texas, United StatesReclutando
GI Alliance - Southlake ( Site 5109)Southlake, Texas, United StatesReclutando
Tyler Research Institute ( Site 5001)Tyler, Texas, United StatesReclutando
Richmond VA Medical Center ( Site 5021)Richmond, Virginia, United StatesReclutando
Washington Gastroenterology - Bellevue ( Site 5040)Bellevue, Washington, United StatesActivo, sin reclutamiento
Swedish Medical Center ( Site 5112)Seattle, Washington, United StatesCompletado
University of Washington ( Site 5115)Seattle, Washington, United StatesReclutando
Washington Gastroenterology - Tacoma ( Site 5004)Tacoma, Washington, United StatesReclutando
Concord Repatriation General Hospital-Gastroenterology and Liver Services ( Site 3202)Concord, New South Wales, AustraliaReclutando
Royal Brisbane and Women's Hospital ( Site 3200)Brisbane, Queensland, AustraliaReclutando
Mater Misericordiae Limited ( Site 3209)Brisbane, Queensland, AustraliaReclutando
Royal Adelaide Hosp - GI Clinical Trials ( Site 3203)Adelaide, South Australia, AustraliaReclutando
Monash Health-Gastroenterology ( Site 3206)Clayton, Victoria, AustraliaReclutando
The Alfred Hospital-Gastroenterology ( Site 3201)Melbourne, Victoria, AustraliaReclutando
Medizinische Universität Wien-Klinik für Innere Medizin III - Abteilung für Gastroenterologie und H ( Site 0202)Vienna, State of Vienna, AustriaReclutando
Medizinische Universitaet Innsbruck-Innere Medizin 1 ( Site 0200)Innsbruck, Tyrol, AustriaReclutando
Uniklinikum Salzburg-Innere Medizin I ( Site 0201)Salzburg, AustriaReclutando
UZ Gent ( Site 0300)Ghent, Oost-Vlaanderen, BelgiumReclutando
UZ Leuven-Gastroenterology - Inflammatory Bowel Disease ( Site 0301)Leuven, Vlaams-Brabant, BelgiumActivo, sin reclutamiento
AZ Delta vzw-Gastroenterology ( Site 0304)Roeselare, West-Vlaanderen, BelgiumReclutando
Hospital de Clinicas de Porto Alegre ( Site 6310)Porto Alegre, Rio Grande do Sul, BrazilReclutando
Hospital Ernesto Dornelles ( Site 6312)Porto Alegre, Rio Grande do Sul, BrazilReclutando
Faculdade de Medicina da UNESP ( Site 6308)Botucatu, São Paulo, BrazilReclutando
Loema Instituto de Pesquisa Clinica ( Site 6302)Campinas, São Paulo, BrazilReclutando
CECIP - Centro de Estudos do Interior Paulista ( Site 6316)Jaú, São Paulo, BrazilReclutando
Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (USP) ( Site 6311)Ribeirão Preto, São Paulo, BrazilReclutando
Pesquisare Saude ( Site 6304)Santo André, São Paulo, BrazilReclutando
Centro de Pesquisa Kaiser - CEPEK ( Site 6306)São José do Rio Preto, São Paulo, BrazilReclutando
BR Trials - Ensaios Clinicos e Consultoria ( Site 6301)São Paulo, BrazilReclutando
Heritage Medical Research Clinic ( Site 0004)Calgary, Alberta, CanadaReclutando
Gastroenterology and internal medicine research institute ( Site 0009)Edmonton, Alberta, CanadaReclutando
Prairie Institute of Liver and Luminal Advanced Research ( Site 0015)Lethbridge, Alberta, CanadaReclutando
Fraser Clinical Trials Inc ( Site 0001)New Westminster, British Columbia, CanadaReclutando
G.I.R.I. GI Research Institute Foundation ( Site 0018)Vancouver, British Columbia, CanadaReclutando
Private Practice - Dr. Bruce Musgrave ( Site 0014)Kentville, Nova Scotia, CanadaReclutando
Barrie GI Associates ( Site 0016)Barrie, Ontario, CanadaReclutando
University Hospital - London Health Sciences Centre ( Site 0002)London, Ontario, CanadaReclutando
London Health Sciences Centre ( Site 0007)London, Ontario, CanadaReclutando
West GTA Research Inc. ( Site 0020)Mississauga, Ontario, CanadaReclutando
ABP Research Services Corp. ( Site 0019)Oakville, Ontario, CanadaReclutando
Toronto Immune & Digestive Health Institute ( Site 0005)Toronto, Ontario, CanadaReclutando
TDDA Inc. ( Site 0006)Vaughan, Ontario, CanadaActivo, sin reclutamiento
Centre de recherche du CISSS de Chaudière-Appalaches - Hôpital Hôtel Dieu de Levis ( Site 0011)Lévis, Quebec, CanadaReclutando
Centre Hospitalier de l'Université de Montréal - Gastroenterology ( Site 0013)Montreal, Quebec, CanadaReclutando
Montreal General Hospital ( Site 0003)Montreal, Quebec, CanadaReclutando
Diex Recherche Quebec ( Site 0008)Québec, Quebec, CanadaCompletado
Hospital hernan henriquez aravena de temuco ( Site 2607)Temuco, Araucania, ChileReclutando
Hospital Clínico Regional Dr. Guillermo Grant Benavente ( Site 2604)Concepción, Biobio, ChileReclutando
Clínica Universidad de Los Andes ( Site 2609)Las Condes, Region M. de Santiago, ChileReclutando
FALP-UIDO ( Site 2600)Santiago, Region M. de Santiago, ChileReclutando
Clínica Alemana de Santiago-Unidad de Investigaciones ( Site 2602)Santiago, Region M. de Santiago, ChileReclutando
Espacio Eme ( Site 2608)Santiago, Region M. de Santiago, ChileReclutando
CECIM ( Site 2603)Santiago, Region M. de Santiago, ChileReclutando
Centro de Investigaciones Clinicas Vina del Mar ( Site 2606)Viña del Mar, Valparaiso, ChileReclutando
Anhui Provincial Hospital ( Site 3922)Hefei, Anhui, ChinaReclutando
Peking University Third Hospital ( Site 3910)Beijing, Beijing Municipality, ChinaReclutando
Chongqing General Hospital ( Site 3940)Chongqing, Chongqing Municipality, ChinaReclutando
The First Affiliated Hospital Of Fujian Medical University ( Site 3916)Fuzhou, Fujian, ChinaReclutando
The First Affiliated hospital of Xiamen University ( Site 3924)Xiamen, Fujian, ChinaReclutando
Zhongshan Hospital Affiliated to Xiamen University ( Site 3923)Xiamen, Fujian, ChinaReclutando
Dongguan People's Hospital ( Site 3933)Dongguan, Guangdong, ChinaReclutando
The First Affiliated Hospital, Sun Yat-sen University ( Site 3901)Guangzhou, Guangdong, ChinaReclutando
The Sixth Affiliated Hospital of Sun Yat-sen University ( Site 3907)Guangzhou, Guangdong, ChinaReclutando
Huizhou Municipal Central Hospital ( Site 3915)Huizhou, Guangdong, ChinaReclutando
Yuebei People's Hospital ( Site 3912)Shaoguan, Guangdong, ChinaReclutando
The University of Hong Kong-Shenzhen Hospital ( Site 3930)Shenzhen, Guangdong, ChinaReclutando
Shenzhen Hospital of Southern Medical University ( Site 3932)Shenzhen, Guangdong, ChinaReclutando
The Second Afilliated Hospital of Hebei Medical University ( Site 3913)Shijiazhuang, Hebei, ChinaReclutando
The Second Affiliated Hospital of Zhengzhou University ( Site 3909)Zhengzhou, Henan, ChinaReclutando
Taihe Hospital ( Site 3944)Shiyan, Hubei, ChinaReclutando
Renmin Hospital of Wuhan University ( Site 3921)Wuhan, Hubei, ChinaReclutando
The Second Xiangya Hospital of Central South University-gastroenterology department ( Site 3905)Changsha, Hunan, ChinaReclutando
Huai'an First People's Hospital ( Site 3948)Huaian, Jiangsu, ChinaReclutando
Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School ( Site 3937)Nanjing, Jiangsu, ChinaReclutando
Zhongda Hospital Southeast University-Gastroenterology ( Site 3911)Nanjing, Jiangsu, ChinaReclutando
Wuxi People's Hospital ( Site 3925)Wuxi, Jiangsu, ChinaReclutando
Yangzhou University Affiliated Hospital ( Site 3947)Yangzhou, Jiangsu, ChinaReclutando
Affiliated Hospital of Jiangsu University ( Site 3919)Zhenjiang, Jiangsu, ChinaReclutando
Changzhou No.2 People's Hospital ( Site 3904)Zhenjiang, Jiangsu, ChinaReclutando
Tangdu Hospital of Fourth Military Medical University of Chinese People's Liberation Army ( Site 3918)Xi'an, Shaanxi, ChinaCompletado
Ruijin Hospital Shanghai Jiaotong University School of Medicine ( Site 3931)Shanghai, Shanghai Municipality, ChinaReclutando
Huashan Hospital of Fudan University ( Site 3946)Shanghai, Shanghai Municipality, ChinaReclutando
Shanghai East Hospital ( Site 3914)Shanghai, Shanghai Municipality, ChinaReclutando
West China Hospital, Sichuan University ( Site 3929)Chengdu, Sichuan, ChinaReclutando
Suining Central Hospital ( Site 3927)Suining, Sichuan, ChinaCompletado
First Affiliated Hospital of Kunming Medical University ( Site 3928)Kunming, Yunnan, ChinaReclutando
Sir Run Run Shaw Hospital of Zhejiang University School of Medicine-GI Medicine ( Site 3902)Hangzhou, Zhejiang, ChinaReclutando
Taizhou Hospital of Zhejiang Province ( Site 3936)Taizhou, Zhejiang, ChinaReclutando
Salud SURA Industriales ( Site 2706)Medellín, Antioquia, ColombiaReclutando
Clinica Medellin S.A ( Site 2705)Medellín, Antioquia, ColombiaReclutando
Fundacion Santa Fe de Bogota ( Site 2703)Bogotá, Cundinamarca, ColombiaReclutando
IMAT S.A.S ( Site 2700)Montería, Departamento de Córdoba, ColombiaReclutando
Oncologos del Occidente ( Site 2702)Pereira, Risaralda Department, ColombiaReclutando
Fundación Valle del Lili ( Site 2704)Cali, Valle del Cauca Department, ColombiaReclutando
Klinička bolnica Merkur ( Site 0503)Zagreb, City of Zagreb, CroatiaCompletado
Klinički bolnički centar Zagreb ( Site 0501)Zagreb, City of Zagreb, CroatiaCompletado
Poliklinika Bates ( Site 0504)Zagreb, City of Zagreb, CroatiaReclutando
Poliklinika Solmed ( Site 0502)Zagreb, City of Zagreb, CroatiaReclutando
Poliklinika Borzan ( Site 0500)Osijek, County of Osijek-Baranja, CroatiaReclutando
Pratia Czech s.r.o. ( Site 0657)Brno, Brno-mesto, CzechiaReclutando
Vojenská Nemocnice Brno-Internal department ( Site 0655)Brno, Brno-mesto, CzechiaReclutando
Nemocnice Slany-Gastroenterologicka a Endoskopicka ambulance ( Site 0651)Slaný, Central Bohemia, CzechiaReclutando
Institut Klinicke a Experimentalni Mediciny-Klinika hepatogastroentrologie ( Site 0654)Prague, Praha 4, CzechiaReclutando
Hepato-Gastroenterologie HK ( Site 0652)Hradec Králové, CzechiaReclutando
ISCARE klinické centrum ( Site 0656)Prague, CzechiaReclutando
Herlev and Gentofte Hospital ( Site 5300)Copenhagen, Capital Region, DenmarkReclutando
Odense Universitetshospital ( Site 5301)Odense C, Region Syddanmark, DenmarkReclutando
CEMDOE - Centro Médico de Diabetes, Obesidad y Especialidades ( Site 2901)Santo Domingo, Nacional, Dominican RepublicReclutando
Tampereen yliopistollinen sairaala ( Site 5401)Tampere, Pirkanmaa, FinlandReclutando
Pohjois-Karjalan Keskussairaala ( Site 5403)Joensuu, Pohjois-Karjala, FinlandReclutando
Turku University Hospital ( Site 5402)Turku, Southwest Finland, FinlandReclutando
Centre Hospitalier Universitaire de Nice - Hôpital l'Archet ( Site 0711)Nice, Alpes-Maritimes, FranceReclutando
CHU Bordeaux Haut-Leveque ( Site 0713)Pessac, Aquitaine, FranceReclutando
Assistance Publique Hôpitaux de Marseille - Hôpital Nord ( Site 0722)Marseille, Bouches-du-Rhone, FranceReclutando
Centre Hospitalier Universitaire Dijon Bourgogne - Hôpital François Mitterrand ( Site 0708)Dijon, Bourgogne-Franche-Comté, FranceReclutando
Centre Hospitalier Universitaire de Reims - Hôpital Robert Debré ( Site 0707)Reims, Champagne-Ardenne, FranceCompletado
CHU Besançon ( Site 0724)Besançon, Doubs, FranceReclutando
Centre Hospitalier de Valence ( Site 0725)Valence, Drome, FranceCompletado
C.H.U. de Nimes. Hopital Caremeau ( Site 0731)Nîmes, Gard, FranceReclutando
CHU Rangueil ( Site 0710)Toulouse, Haute-Garonne, FranceReclutando
Hopital Beaujon ( Site 0729)Clichy, Hauts-de-Seine, FranceReclutando
CMC Ambroise Paré Hartmann - Institut des MICI ( Site 0723)Neuilly-sur-Seine, Hauts-de-Seine, FranceReclutando
Clinique des Cèdres ( Site 0732)Échirolles, Isere, FranceReclutando
CHU SAINT ELOI ( Site 0701)Montpellier, Languedoc-Roussillon, FranceActivo, sin reclutamiento
Centre Hospitalier Universitaire de Nantes - L' Hopital l'hôtel-Dieu ( Site 0705)Nantes, Loire-Atlantique, FranceReclutando
Centre Hospitalier Régional Universitaire de Nancy - Hôpitaux de Brabois ( Site 0717)Vandœuvre-lès-Nancy, Meurthe-et-Moselle, FranceReclutando
Hopital Claude Huriez - CHU de Lille ( Site 0715)Lille, Nord, FranceReclutando
centre hospitalier lyon sud ( Site 0716)Pierre-Bénite, Rhone, FranceReclutando
CHU d'Amiens-Picardie - Hôpital Sud ( Site 0709)Amiens, Somme, FranceReclutando
Hopital Henri Mondor ( Site 0730)Créteil, Val-de-Marne, FranceReclutando
Hôpital Saint Antoine ( Site 0721)Paris, FranceReclutando
Hôpitaux Universitaires Paris Sud - Hôpital Bicêtre ( Site 0702)Le Kremlin-Bicêtre, Île-de-France Region, FranceCompletado
LTD High Technology Hospital Medcenter ( Site 0802)Batumi, Adjara, GeorgiaReclutando
Caucasus Medical Centre ( Site 0801)Tbilisi, Adjara, GeorgiaReclutando
New Hospitals ( Site 0800)Tbilisi, GeorgiaReclutando
Caraps Medline ( Site 0803)Tbilisi, GeorgiaReclutando
Siloah St. Trudpert Klinikum-Zentrum für Innere Medizin ( Site 0992)Pforzheim, Baden-Wurttemberg, GermanyReclutando
Klinikum der Universität München Großhadern ( Site 0990)München, Bavaria, GermanyReclutando
klinikum rechts der isar der technischen universität münchen ( Site 0989)München, Bavaria, GermanyReclutando
Universitaetsklinikum Ulm. ( Site 0994)Ulm, Bavaria, GermanyReclutando
Medizinische Hochschule Hannover ( Site 0999)Hanover, Lower Saxony, GermanyReclutando
Klinikum Lüneburg ( Site 0991)Lüneburg, Lower Saxony, GermanyReclutando
Universitätsmedizin Rostock ( Site 0993)Rostock, Mecklenburg-Vorpommern, GermanyReclutando
Evangelisches Krankenhaus Kalk gGmbH ( Site 0986)Cologne, North Rhine-Westphalia, GermanyCompletado
Stadtische Kliniken Duisburg, Abtlg. Innere Medizin ( Site 0985)Duisburg, North Rhine-Westphalia, GermanyReclutando
Gastroenterologische Gemeinschaftspraxis Minden ( Site 0998)Minden, North Rhine-Westphalia, GermanyReclutando
Medizinisches Versorgungszentrum Portal 10 ( Site 0988)Münster, North Rhine-Westphalia, GermanyCompletado
Magen Darm Zentrum Remscheid ( Site 0984)Remscheid, North Rhine-Westphalia, GermanyReclutando
St. Marien und St. Annastift Krankenhaus ( Site 0987)Ludwighafen Am Rhein, Rhineland-Palatinate, GermanyReclutando
Universitätsklinikum Leipzig ( Site 0997)Leipzig, Saxony, GermanyReclutando
Universitaetsklinikum Schleswig-Holstein Campus Kiel ( Site 0995)Kiel, Schleswig-Holstein, GermanyReclutando
Charité Campus Virchow-Klinikum ( Site 0996)Berlin, GermanyReclutando
Universitätsklinikum Brandenburg an der Havel ( Site 0903)Brandenburg, GermanyReclutando
Evangelismos General Hospital of Athens ( Site 1002)Athens, Attica, GreeceReclutando
THORACIC GENERAL HOSPITAL OF ATHENS "I SOTIRIA"-3rd Dept of Internal Medicine and Laboratory, Oncol ( Site 1004)Athens, Attica, GreeceReclutando
General Hospital of Nikaia-Piraeus "Agios Panteleimon" ( Site 1003)Nikaia Piraeus, Attica, GreeceReclutando
Ippokrateio General Hospital of Thessaloniki ( Site 1001)Thessaloniki, Central Macedonia, GreeceReclutando
University General Hospital of Heraklion-GASTROENTEROLOGY & HEPATOLOGY ( Site 1000)Heraklion, Crete, GreeceReclutando
Queen Mary Hospital ( Site 3300)Hksar, Hong KongReclutando
Békés Megyei Központi Kórház Dr. Réthy Pál Tagkórház-4. Belgyogyaszat Gasztroenterologia ( Site 1105)Békéscsaba, Bekescsaba, HungaryReclutando
Heves Vármegyei Markhot Ferenc Oktatókórház és Rendelőintézet ( Site 1117)Eger, Heves County, HungaryCompletado
Gyöngyösi Bugát Pál Kórház ( Site 1111)Gyöngyös, Heves County, HungaryReclutando
Komarom-Esztergom Varmegyei Szent Borbala Korhaz ( Site 1115)Tatabánya, Komárom-Esztergom, HungaryReclutando
VeszLife Magánklinika ( Site 1102)Veszprém, Veszprém megye, HungaryReclutando
Clinexpert Kft.-Clinexpert Budapest ( Site 1108)Budapest, HungaryReclutando
Synexus Magyarorszag Kft. (Budapest DRS) ( Site 1107)Budapest, HungaryCompletado
Semmelweis Egyetem ( Site 1118)Budapest, HungaryReclutando
Eszak-Pesti Centrumkorhaz-Honvedkorhaz ( Site 1100)Budapest, HungaryCompletado
Pannónia Magánorvosi Centrum ( Site 1103)Budapest, HungaryReclutando
Beaumont Hospital, Dublin ( Site 5601)Dublin, IrelandCompletado
Emek Medical Center ( Site 1206)Afula, IsraelReclutando
Barzilai Medical Center ( Site 1209)Ashkelon, IsraelReclutando
Rambam Health Care Campus ( Site 1201)Haifa, IsraelReclutando
Bnai Zion Medical Center ( Site 1203)Haifa, IsraelReclutando
Edith Wolfson Medical Center ( Site 1204)Holon, IsraelReclutando
Shaare Zedek Medical Center ( Site 1208)Jerusalem, IsraelReclutando
Meir Medical Center. ( Site 1202)Kfar Saba, IsraelReclutando
Rabin Medical Center ( Site 1207)Petah Tikva, IsraelReclutando
Sheba Medical Center ( Site 1200)Ramat Gan, IsraelReclutando
A.O.U.C. Policlinico di Bari ( Site 1306)Bari, Apulia, ItalyReclutando
Policlinico Universitario Monserrato-SC Gastroenterologia ( Site 1313)Monserrato, Cagliari, ItalyReclutando
Fondazione Policlinico Tor Vergata ( Site 1307)Rome, Lazio, ItalyActivo, sin reclutamiento
Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico-Gastroenterology and Endoscopy Unit ( Site 1304)Milan, Lombardy, ItalyReclutando
Istituto Clinico Humanitas-IBD center ( Site 1309)Rozzano, Lombardy, ItalyReclutando
A.O.R.N. Ospedale dei Colli - Monaldi V. ( Site 1310)Naples, Napoli, ItalyReclutando
Ospedale Mauriziano - Gastroenterology Unit ( Site 9000)Turin, Piedmont, ItalyReclutando
Ospedale "Felice Lotti" Di Pontedera ( Site 1311)Pontedera, Pisa, ItalyReclutando
Az. Osp. Ospedali Riuniti VILLA SOFIA-CERVELLO-U.O.S.D. Malattie Infiammatorie Croniche Intestinali ( Site 1302)Palermo, Sicily, ItalyReclutando
Azienda Ospedaliera Universitaria Careggi-MICI ( Site 9002)Florence, Tuscany, ItalyReclutando
Ospedale Sacro Cuore Don G. Calabria-IBD Unit ( Site 1303)Negrar, Verona, ItalyReclutando
IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola ( Site 1308)Bologna, ItalyReclutando
Azienda Ospedaliera Universitaria Di Messina G. Martino ( Site 1314)Messina, ItalyReclutando
Ospedale San Raffaele-Gastroenterology and Gastrointestinal Endoscopy ( Site 1300)Milan, ItalyReclutando
Fondazione Policlinico Universitario Agostino Gemelli IRCCS -Dipartimento di Medicina Interna e Gas ( Site 1312)Roma, ItalyReclutando
Aichi Medical University Hospital ( Site 3429)Nagakute, Aichi-ken, JapanCompletado
Nagoya University Hospital ( Site 3445)Nagoya, Aichi-ken, JapanReclutando
Nagoya City University Hospital ( Site 3446)Nagoya, Aichi-ken, JapanCompletado
Tokatsu Tsujinaka Hospital ( Site 3403)Abiko, Chiba, JapanReclutando
Tsujinaka Hospital - Kashiwanoha ( Site 3402)Kashiwa, Chiba, JapanReclutando
Toho University Sakura Medical Center ( Site 3413)Sakura, Chiba, JapanReclutando
Kurume University Hospital ( Site 3419)Kurume, Fukuoka, JapanReclutando
Gunma University Hospital ( Site 3432)Maebashi, Gunma, JapanReclutando
National Hospital Organization Fukuyama Medical Center ( Site 3442)Fukuyama, Hiroshima, JapanCompletado
Sapporo Tokushukai Hospital ( Site 3427)Sapporo, Hokkaido, JapanActivo, sin reclutamiento
Sapporo Medical University Hospital ( Site 3460)Sapporo, Hokkaido, JapanCompletado
Medical Corporation Sapporo IBD Clinic ( Site 3420)Sapporo, Hokkaido, JapanActivo, sin reclutamiento
Sapporohigashi Tokushukai Hospital ( Site 3441)Sapporo, Hokkaido, JapanReclutando
Hyogo Medical University Hospital ( Site 3430)Nishinomiya, Hyōgo, JapanReclutando
Hitachi General Hospital ( Site 3438)Hitachi, Ibaraki, JapanReclutando
Tsuchiura Kyodo General Hospital ( Site 3463)Tsuchiura, Ibaraki, JapanCompletado
Tsukuba Memorial Hospital ( Site 3461)Tsukuba, Ibaraki, JapanCompletado
Kanazawa University Hospital ( Site 3436)Kanazawa, Ishikawa-ken, JapanReclutando
Iwate Medical University Hospital ( Site 3457)Shiwa-gun, Iwate, JapanReclutando
Gokeikai Ofuna Chuo Hospital ( Site 3412)Kamakura, Kanagawa, JapanReclutando
St. Marianna University Hospital ( Site 3440)Kawasaki, Kanagawa, JapanReclutando
Matsushima Hospital ( Site 3450)Yokohama, Kanagawa, JapanReclutando
Yokohama City University Medical Center ( Site 3439)Yokohama, Kanagawa, JapanReclutando
Mie University Hospital ( Site 3405)Tsu, Mie-ken, JapanCompletado
Tohoku University Hospital ( Site 3447)Sendai, Miyagi, JapanReclutando
University of the Ryukyus Hospital ( Site 3459)Ginowan, Okinawa, JapanReclutando
Kansai Medical University Hospital ( Site 3409)Hirakata, Osaka, JapanReclutando
Saitama Medical Center ( Site 3452)Kawagoe, Saitama, JapanReclutando
Hamamatsu University Hospital ( Site 3449)Hamamatsu, Shizuoka, JapanReclutando
Matsuda Hospital ( Site 3404)Hamamatsu, Shizuoka, JapanReclutando
National Hospital Organization Shizuoka Medical Center ( Site 3401)Shimizu, Shizuoka, JapanReclutando
Institute of Science Tokyo Hospital ( Site 3437)Bunkyō, Tokyo, JapanReclutando
Ginza Central Clinic ( Site 3407)Chūō, Tokyo, JapanCompletado
Kitasato University Kitasato Institute Hospital ( Site 3458)Minato, Tokyo, JapanReclutando
Toranomon Hospital ( Site 3433)Minato-ku, Tokyo, JapanReclutando
Kyorin University Hospital ( Site 3443)Mitaka, Tokyo, JapanReclutando
The Jikei University Hospital ( Site 3414)Mitato, Tokyo, JapanReclutando
Tokyo Medical University Hospital ( Site 3456)Shinjuku, Tokyo, JapanReclutando
National Center for Global Health and Medicine ( Site 3423)Shinjuku, Tokyo, JapanReclutando
Yamanashi Prefectural Central Hospital ( Site 3435)Kofu, Yamanashi, JapanReclutando
Fukuoka University Hospital ( Site 3417)Fukuoka, JapanReclutando
Japanese Red Cross Fukuoka Hospital ( Site 3462)Fukuoka, JapanCompletado
Hiroshima University Hospital ( Site 3418)Hiroshima, JapanReclutando
Kagoshima University Hospital ( Site 3425)Kagoshima, JapanCompletado
Kagoshima IBD Gastroenterology Clinic ( Site 3428)Kagoshima, JapanReclutando
Coloproctology Center Takano Hospital ( Site 3466)Kumamoto, JapanReclutando
University Hospital,Kyoto Prefectural University of Medicine ( Site 3406)Kyoto, JapanReclutando
National Hospital Organization Kyoto Medical Center ( Site 3411)Kyoto, JapanReclutando
Okayama University Hospital ( Site 3454)Okayama, JapanCompletado
Kinshukai Grand Front Osaka Medical Clinic ( Site 3408)Osaka, JapanReclutando
National Hospital Organization Osaka National Hospital ( Site 3453)Osaka, JapanReclutando
Saga University Hospital ( Site 3424)Saga, JapanActivo, sin reclutamiento
Tokyo Yamate Medical Center ( Site 3415)Tokyo, JapanReclutando
Toyama Prefectural Central Hospital ( Site 3410)Toyama, JapanReclutando
Yamagata University Hospital ( Site 3426)Yamagata, JapanReclutando
Pauls Stradins Clinical University Hospital ( Site 5903)Riga, LatviaReclutando
SIA M & M Centrs ( Site 5902)Adazi, Ādaži, LatviaReclutando
Hospital of Lithuanian University of Health Sciences Kauno klinikos-Gastroenterology ( Site 6000)Kaunas, Kaunas County, LithuaniaReclutando
VILNIUS UNIVERSITY HOSPITAL SANTAROS KLINIKOS-Department of Clinical Trials and Pharmacology ( Site 6001)Vilnius, LithuaniaReclutando
Hospital Sultanah Aminah ( Site 6104)Johor Bahru, Johor, MalaysiaReclutando
Hospital Universiti Sains Malaysia ( Site 6103)Kubang Kerian, Kelantan, MalaysiaReclutando
University Malaya Medical Centre ( Site 6101)Lembah Pantai, Kuala Lumpur, MalaysiaReclutando
Sarawak General Hospital ( Site 6102)Kuching, Sarawak, MalaysiaReclutando
Hospital Ampang ( Site 6106)Ampang, Selangor, MalaysiaReclutando
Morales Vargas Centro de Investigacion S. C. ( Site 3101)León, Guanajuato, MexicoReclutando
Centro Medico Clinico Quirurgico Especializado en Investigación ( Site 3106)Tlajomulco de Zúñiga, Jalisco, MexicoReclutando
Centro de Investigación y Gastroenterología - S.C. ( Site 3102)Benito Juarez Ciudad de Mexico, Mexico City, MexicoReclutando
Medica Sur-Clinica de Enfermedades Digestivas y Obesidad ( Site 3104)Mexico City, Mexico City, MexicoCompletado
JM Research SC ( Site 3109)Cuernavaca, Morelos, MexicoReclutando
Hospital Universitario "Dr. Jose Eleuterio Gonzalez"-Gastroenterología ( Site 3100)Monterrey, Nuevo León, MexicoReclutando
Servicios de Oncología Médica Integral, S.A de C.V. ( Site 3108)San Pedro Garza García, Nuevo León, MexicoReclutando
Centro de Investigacion Clinica de Oaxaca ( Site 3105)Oaxaca City, Oaxaca, MexicoReclutando
Medical Care and Research SA de CV-GASTROENTEROLOGY ( Site 3110)Mérida, Yucatán, MexicoReclutando
Scientia Investigacion Clinica S.C. ( Site 3114)Chihuahua City, MexicoReclutando
Radboudumc ( Site 1505)Nijmegen, Gelderland, NetherlandsReclutando
ETZ Elisabeth ( Site 1501)Tilburg, North Brabant, NetherlandsReclutando
Ziekenhuis Bernhoven ( Site 1508)Uden, North Brabant, NetherlandsReclutando
Amsterdam UMC, locatie VUmc-IBD Trial Unit ( Site 1500)Amsterdam, North Holland, NetherlandsReclutando
Erasmus Medisch Centrum ( Site 1504)Rotterdam, South Holland, NetherlandsReclutando
Franciscus Gasthuis & Vlietland, Locatie Gasthuis ( Site 1503)Rotterdam, South Holland, NetherlandsReclutando
University Medical Center Groningen ( Site 1506)Groningen, NetherlandsReclutando
Universitair Medisch Centrum Utrecht ( Site 1502)Utrecht, NetherlandsReclutando
Dunedin Hospital ( Site 3505)Dunedin, Otago, New ZealandReclutando
Hutt Valley District Health board HVDHB ( Site 3500)Lower Hutt, Wellington Region, New ZealandReclutando
Aotearoa Clinical Trials ( Site 3501)Auckland, New ZealandReclutando
Investigaciones Clínicas / Instituto de Ginecología y Reproducción ( Site 3002)Lima, PeruReclutando
Hospital Cayetano Heredia ( Site 3003)Lima, PeruReclutando
Hospital Nacional Edgardo Rebagliati Martins-Aparato Digestivo ( Site 0154)Lima, PeruReclutando
Pratia S.A. Pratia Poznan ( Site 1603)Poznan, Greater Poland Voivodeship, PolandReclutando
EMC Instytut Medyczny S.A,Prywatna Lecznica Certus Ambulatoria,Prywatna Lecznica Certus Szpital Nr1 ( Site 1605)Poznan, Greater Poland Voivodeship, PolandReclutando
Twoja Przychodnia Poznanskie Centrum Medyczne Sp. z o.o.,Twoja Przychodnia PCM ( Site 1632)Poznan, Greater Poland Voivodeship, PolandReclutando
NZOZ Centrum Medyczne KERmed ( Site 1641)Bydgoszcz, Kuyavian-Pomeranian Voivodeship, PolandReclutando
Gastromed Sp. z o. o. ( Site 1619)Torun, Kuyavian-Pomeranian Voivodeship, PolandReclutando
Centrum Medyczne Plejady ( Site 1627)Krakow, Lesser Poland Voivodeship, PolandReclutando
FutureMeds Krakow ( Site 1628)Krakow, Lesser Poland Voivodeship, PolandReclutando
PROMED P. LACH R. GLOWACKI SP. J. ( Site 1636)Krakow, Lesser Poland Voivodeship, PolandReclutando
Allmedica ( Site 1602)Nowy Targ, Lesser Poland Voivodeship, PolandReclutando
Medicome Sp. z o.o ( Site 1635)Oświęcim, Lesser Poland Voivodeship, PolandReclutando
Amicare ( Site 1620)Jelenia Góra, Lower Silesian Voivodeship, PolandActivo, sin reclutamiento
Planetmed ( Site 1600)Wroclaw, Lower Silesian Voivodeship, PolandReclutando
Vistamed & Vertigo Sp. z o.o. ( Site 1621)Wroclaw, Lower Silesian Voivodeship, PolandReclutando
Melita Medical Sp. z o.o. ( Site 1607)Wroclaw, Lower Silesian Voivodeship, PolandReclutando
Penta Hospitals Przychodnie Wrocław Wejherowska ( Site 1601)Wroclaw, Lower Silesian Voivodeship, PolandReclutando
Medrise Sp. z o.o. ( Site 1626)Lublin, Lublin Voivodeship, PolandReclutando
Uniwersytecki Szpital Kliniczny nr 4 w Lublinie, Kliniczny Oddział Gastroenterologii, Hepatologii i ( Site 1615)Lublin, Lublin Voivodeship, PolandReclutando
ETG Zamosc ( Site 1631)Zamość, Lublin Voivodeship, PolandReclutando
EB Group Sp. Z o.o. Centrum Zdrowia MDM ( Site 1618)Warsaw, Masovian Voivodeship, PolandReclutando
ETG Warszawa ( Site 1629)Warsaw, Masovian Voivodeship, PolandReclutando
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Gastroenterologii Onkologiczne ( Site 1624)Warsaw, Masovian Voivodeship, PolandReclutando
Vivamed Sp. z o.o. ( Site 1623)Warsaw, Masovian Voivodeship, PolandReclutando
WIP Warsaw IBD Point Profesor Kierkuś ( Site 1622)Warsaw, Masovian Voivodeship, PolandReclutando
Twoja Przychodnia Opolskie Centrum Medyczne ( Site 1633)Opole, Opole Voivodeship, PolandReclutando
Endoskopia Sp. z.o.o. ( Site 1637)Sopot, Pomeranian Voivodeship, PolandReclutando
M2M ( Site 1630)Chorzów, Silesian Voivodeship, PolandReclutando
H-T Centrum Medyczne Endoterapia ( Site 1610)Tychy, Silesian Voivodeship, PolandReclutando
Twoja Przychodnia - Szczecinskie Centrum Medyczne ( Site 1612)Szczecin, West Pomeranian Voivodeship, PolandReclutando
Sonomed Sp. z o. o. ( Site 1617)Szczecin, West Pomeranian Voivodeship, PolandReclutando
IP Clinic ( Site 1638)Lodz, Łódź Voivodeship, PolandReclutando
Centrum Medyczne Med-Gastr Sp. z o.o. ( Site 1616)Lodz, Łódź Voivodeship, PolandReclutando
AmiCare Sp. z o.o. Sp. k. ( Site 1608)Lodz, Łódź Voivodeship, PolandReclutando
Unidade Local de Saúde do Alto Ave - Hospital Senhora da Oliveira ( Site 1704)Guimarães, Braga District, PortugalReclutando
Unidade Local de Saude do Algarve - Hospital de Portimão ( Site 1700)Portimão, Faro District, PortugalReclutando
Unidade Local de Saude da Região de Leiria - Hospital Santo André ( Site 1706)Leiria, PortugalReclutando
Hospital da Luz Lisboa ( Site 1707)Lisbon, PortugalReclutando
Hospital dos Lusíadas Lisboa ( Site 1701)Lisbon, PortugalReclutando
ULSAM - Hospital de Santa Luzia ( Site 1703)Viana do Castelo, PortugalReclutando
Unidade Local de Saude Dão-Lafões - Hospital de São Teotónio ( Site 1702)Viseu, PortugalReclutando
MEMORIAL HEALTHCARE INTERNATIONAL S.R.L ( Site 1806)Bucharest, Bucharest, RomaniaReclutando
Fundeni Clinical Institute-Gastroenterology and Hepatology Center ( Site 1808)Bucharest, Bucharest, RomaniaReclutando
GastroMed ( Site 1809)Cluj-Napoca, Cluj, RomaniaReclutando
Spitalul Clinic Judetean Mures-Gastroenterology ( Site 1807)Târgu Mureş, Mureș County, RomaniaReclutando
ASOCIATIA ONCOHELP ( Site 1805)Timișoara, Timiș County, RomaniaReclutando
Monza Ares SRL ( Site 1804)Bucharest, RomaniaReclutando
King Abdullah Medical City Specialist Hospital ( Site 5230)Mecca, Makkah Al Mukarramah, Saudi ArabiaReclutando
King Abdul Aziz Medical City - AlRiyadh ( Site 5210)Riyadh, Riyadh Region, Saudi ArabiaReclutando
King Saud University Medical City ( Site 5220)Riyadh, Riyadh Region, Saudi ArabiaReclutando
King Faisal Specialist Hospital and Research Center ( Site 5200)Riyadh, Riyadh Region, Saudi ArabiaReclutando
Clinical Hospital Center Dragisa Misovic ( Site 1906)Belgrade, Beograd, SerbiaReclutando
Clinical Hospital Center Zvezdara-Gastroenterology and hepatology Department ( Site 1903)Belgrade, Beograd, SerbiaReclutando
University Medical Center "Bezanijska kosa"-Gastroenterology and hepatology ( Site 1900)Belgrade, Beograd, SerbiaReclutando
Zemun Medical Centre ( Site 1910)Zemun, Beograd, SerbiaReclutando
General Hospital "Djordje Joanovic" ( Site 1905)Zrenjanin, Srednjebanatski Okrug, SerbiaReclutando
Clinical Center Kragujevac ( Site 1904)Kragujevac, Sumadijski Okrug, SerbiaReclutando
Singapore General Hospital ( Site 6202)Singapore, Central Singapore, SingaporeReclutando
Tan Tock Seng Hospital-Gastroenterology and Hepatology ( Site 6201)Singapore, Central Singapore, SingaporeReclutando
Changi General Hospital ( Site 6203)Singapore, South East, SingaporeCompletado
Fakultna nemocnica s poliklinikou F.D.Roosevelta Banska Bystrica-Gastroenterologicke oddelenie ( Site 2002)Banská Bystrica, Banská Bystrica Region, SlovakiaReclutando
Cliniq s.r.o. ( Site 2001)Bratislava, Bratislava Region, SlovakiaCompletado
KM Management ( Site 2000)Nitra, Nitra Region, SlovakiaReclutando
GASTRO I ( Site 2004)Prešov, Presov, SlovakiaReclutando
Gastro LM ( Site 2005)Prešov, Presov, SlovakiaReclutando
Wits Clinical Research ( Site 4004)Johannesburg, Gauteng, South AfricaReclutando
Wits Clinical Research-Chris Hani Baragwanath Hospital ( Site 4005)Soweto, Gauteng, South AfricaReclutando
Panorama Medical Centre ( Site 4001)Cape Town, Western Cape, South AfricaReclutando
Spoke Research ( Site 4003)Cape Town, Western Cape, South AfricaReclutando
Life Kingsbury Hospital ( Site 4000)Cape Town, Western Cape, South AfricaReclutando
Private Practice - Dr. M.N. Rajabally ( Site 4007)Plumstead, Western Cape, South AfricaReclutando
Wonju Severance Christian Hospital-Internal Medicine ( Site 3600)Wŏnju, Kang-won-do, South KoreaReclutando
Korea University Ansan Hospital ( Site 3617)Ansan-si, Kyonggi-do, South KoreaReclutando
The Catholic University Of Korea St. Vincent's Hospital-Gastroenterology ( Site 3608)Suwon, Kyonggi-do, South KoreaCompletado
Dong-A University Hospital ( Site 3601)Busan, Pusan-Kwangyokshi, South KoreaReclutando
Inje University Haeundae Paik Hospital ( Site 3605)Haeundae-gu, Pusan-Kwangyokshi, South KoreaReclutando
Chung-Ang University Hospital ( Site 3606)Dongjak-gu, Seoul, South KoreaReclutando
Kyungpook National Univ.Hospital ( Site 3616)Daegu, Taegu-Kwangyokshi, South KoreaReclutando
Yeungnam Univeristy Medical Center ( Site 3610)Daegu, Taegu-Kwangyokshi, South KoreaReclutando
Keimyung University Dongsan Medical Center ( Site 3614)Daegu, Taegu-Kwangyokshi, South KoreaReclutando
The Catholic University of Korea, Daejeon St. Mary's Hospital ( Site 3604)Daejeon, Taejon-Kwangyokshi, South KoreaReclutando
Kyung Hee University Hospital ( Site 3611)Seoul, South KoreaReclutando
Seoul National University Hospital ( Site 3607)Seoul, South KoreaReclutando
Kangbuk Samsung Hospital-Internal Medicine ( Site 3612)Seoul, South KoreaReclutando
The Catholic University of Korea, Eunpyeong St. Mary's Hospital ( Site 3602)Seoul, South KoreaReclutando
Severance Hospital, Yonsei University Health System-Department of Internal Medicine ( Site 3603)Seoul, South KoreaReclutando
Asan Medical Center ( Site 3609)Seoul, South KoreaReclutando
Samsung Medical Center ( Site 3613)Seoul, South KoreaReclutando
Hospital Germans Trias i Pujol ( Site 2101)Badalona, Barcelona, SpainReclutando
HOSPITAL CLÍNIC DE BARCELONA-ICMDM - Clinical Institute of Digestive and Metabolic Diseases ( Site 2112)Barcelona, Catalonia, SpainReclutando
Complejo Hospitalario Universitario de Ferrol ( Site 2114)A Coruña, La Coruna, SpainReclutando
Hospital Universitario Puerta de Hierro ( Site 2102)Majadahonda, Madrid, SpainReclutando
Hospital Universitario de Torrejón ( Site 2108)Torrejón de Ardoz, Madrid, SpainReclutando
Hospital Universitario La Paz ( Site 2100)Madrid, SpainReclutando
Hospital Montecelo. Complexo Hospitalario de Pontevedra ( Site 2107)Pontevedra, SpainReclutando
Hospital Universitario Nuestra Senora de la Candelaria ( Site 2105)Santa Cruz de Tenerife, SpainReclutando
HOSPITAL CLINICO DE VALENCIA-MEDICINA DIGESTIVA ( Site 2103)Valencia, SpainReclutando
Hospital Universitari i Politecnic La Fe ( Site 2111)Valencia, SpainReclutando
Hospital Universitario Miguel Servet ( Site 2104)Zaragoza, SpainReclutando
Danderyds Sjukhus ( Site 5501)Danderyd, Stockholm County, SwedenReclutando
Karolinska Universitetssjukhuset Solna ( Site 5500)Stockholm, Stockholm County, SwedenReclutando
Universitetssjukhuset i Linköping ( Site 5502)Linköping, Östergötland County, SwedenReclutando
University Hospital Basel-Gastroenterology and Hepatology ( Site 2204)Basel, Canton of Basel-City, SwitzerlandReclutando
INTESTO-Gastroenterologische Praxis / Crohn-Colitis Zentrum Bern ( Site 2202)Bern, Canton of Bern, SwitzerlandReclutando
Cantonal Hospital St.Gallen-Klinik für Gastroenterologie / Hepatologie ( Site 2201)Sankt Gallen, Canton of St. Gallen, SwitzerlandReclutando
UniversitätsSpital Zürich-Gastroenterologie & Hepatologie ( Site 2200)Zurich, Canton of Zurich, SwitzerlandReclutando
National Taiwan University BioMedical Park Hospital ( Site 3702)Zhubei, Hsinchu, TaiwanReclutando
National Taiwan University Hospital-Internal Medicine ( Site 3700)Taipei, TaiwanReclutando
Chang Gung Medical Foundation-Linkou Branch ( Site 3701)Taoyuan, TaiwanReclutando
Ege Universitesi Hastanesi ( Site 2302)Bornova, İzmir, Turkey (Türkiye)Activo, sin reclutamiento
Hacettepe Universitesi Tip Fakultesi Hastanesi ( Site 2300)Ankara, Turkey (Türkiye)Reclutando
ANKARA UNIVERSITY IBNI SINA HOSPITAL-Gastroenterology ( Site 2303)Ankara, Turkey (Türkiye)Completado
Ankara Bilkent Şehir Hastanesi-Gastroenterology ( Site 2301)Ankara, Turkey (Türkiye)Reclutando
Antalya Egitim ve Arastırma Hastanesi ( Site 2304)Antalya, Turkey (Türkiye)Reclutando
Eskisehir Osmangazi University Faculty of Medicine ( Site 2308)Eskişehir, Turkey (Türkiye)Completado
Istanbul Universitesi Cerrahpasa Tip Fakultesi Hastanesi ( Site 2306)Istanbul, Turkey (Türkiye)Completado
Marmara Univetsitesi Pendik Egitim ve Arastirma Hastanesi ( Site 2305)Istanbul, Turkey (Türkiye)Reclutando
Kocaeli University Medical Faculty Hospital ( Site 2309)Kocaeli, Turkey (Türkiye)Reclutando
Communal non-profit enterprise "Regional clinical hospital of Ivano-Frankivsk Regional Council" ( Site 5815)Ivano-Frankivsk, Ivano-Frankivsk Oblast, UkraineReclutando
Medical Center of Limited ( Site 5806)Kyiv, Kyivska Oblast, UkraineReclutando
Center of Family Medicine Plus ( Site 5803)Kyiv, Kyivska Oblast, UkraineReclutando
Communal Non-profit Enterprise of Lviv Regional Council "Lviv Regional Clinical Hospital"-proctology ( Site 5809)Lviv, Lviv Oblast, UkraineReclutando
Limited liability company "Medical center Health Clinic" ( Site 5807)Vinnytsia, Vinnytsia Oblast, UkraineReclutando
Municipal Nonprofit Enterprise "Vinnytsia Regional Clinical Hospital n.a. M. I. Pyrohov of Vinnytsia ( Site 5814)Vinnytsia, Vinnytsia Oblast, UkraineReclutando
Clinic of Scientific and Research Institute of Invalid Rehabilitation of VNMU n.a. M.I.Pyrohov ( Site 5812)Vinnytsia, Vinnytsia Oblast, UkraineReclutando
Communal Non-Commercial Enterprise "Vinnytsia City Clinical -Clinical Therapeutic Department #1 ( Site 5811)Vinnytsia, Vinnytsia Oblast, UkraineReclutando
Municipal Enterprise "Volyn Regional Clinical Hospital" of Volyn Regional Council ( Site 5813)Lutsk, Volyn Oblast, UkraineReclutando
Medical Center "Universal Clinic "Oberig" of Limited Liability Company "Kapytal" ( Site 5800)Kyiv, UkraineReclutando
Dobrobut Medical Center ( Site 5801)Kyiv, UkraineReclutando
Medical Center of Private Enterprise "Sygma" ( Site 5808)Kyiv, UkraineReclutando
Addenbrooke's Hospital ( Site 2400)Cambridge, Cambridgeshire, United KingdomReclutando
Royal Devon & Exeter Hospital ... ( Site 2407)Exeter, Devon, United KingdomActivo, sin reclutamiento
Doncaster Royal Infirmary ( Site 2401)Doncaster, England, United KingdomReclutando
Huddersfield Royal Infirmary ( Site 2409)Huddersfield, England, United KingdomReclutando
Whipps Cross University Hospital-Clinical Research Unit ( Site 2404)London, England, United KingdomReclutando
Southampton General Hospital ( Site 2402)Southampton, Hampshire, United KingdomReclutando
University College London Hospital-Clinical Research Facility ( Site 2405)London, London, City of, United KingdomReclutando
The John Radcliffe Hospital ( Site 2406)Oxford, Oxfordshire, United KingdomReclutando
Southmead Hospital ( Site 2403)Bristol, South Gloucestershire, United KingdomReclutando
Walsall Manor Hospital ( Site 2410)West Midlands, Walsall, United KingdomActivo, sin reclutamiento

Equipo y fechas

Patrocinador principal
Merck Sharp & Dohme LLC
Inicio del estudio
5 jun 2024 Real
Finalización primaria
30 oct 2028 Estimado
Finalización del estudio
12 nov 2029 Estimado
Primera publicación
28 may 2024 Real
Última actualización
10 nov 2026 Real

Contactos oficiales del estudio

Toll Free NumberCONTACTTrialsites@msd.com1-888-577-8839
Título oficial del estudio

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Program to Evaluate the Efficacy and Safety of Tulisokibart in Participants With Moderately to Severely Active Crohn's Disease

EL PRÓXIMO PASO, CON APOYO HUMANO

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Fuente: API v2 de ClinicalTrials.gov. Patrocinadores e investigadores envían la información. La NLM no aprueba la seguridad ni la ciencia de todos los estudios registrados. Aviso del registro.

Consultado: 11 nov 2026 · Última actualización del registro: 10 nov 2026